SCHEMBL2835097

SCHEMBL2835097

CC(C)C(=Cc1ccccc1)c1ccccc1

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
AKR1C1 Q04828 1/20 0.45
ALDH1A1 P00352 2/20 0.42
TSHR P16473 1/20 0.42
AKR1C3 P42330 1/20 0.42
PRMT1 Q99873 1/20 0.41
ESR1 P03372 1/20 0.41
MTNR1A P48039 2/20 0.40
MTNR1B P49286 2/20 0.40
MEN1 O00255 2/20 0.40
KMT2A Q03164 2/20 0.40
CYP19A1 P11511 1/20 0.39
CYP11B2 P19099 1/20 0.39
LMNA P02545 3/20 0.39
MAPT P10636 3/20 0.39
HTT P42858 3/20 0.39
KDM4E B2RXH2 1/20 0.39
POLB P06746 1/20 0.39
HPGD P15428 1/20 0.39
MAPK1 P28482 1/20 0.39
FBP1 P09467 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5960470 1.00 AKR1C1 (0.45) AKR1C1ALDH1A1TSHRAKR1C3PRMT1
SCHEMBL13461645 0.87 CYP19A1 (0.44) AKR1C1ALDH1A1TSHRAKR1C3PRMT1
SCHEMBL9194664 0.83 ALDH1A1 (0.42) AKR1C1ALDH1A1TSHRAKR1C3ESR1
SCHEMBL16500484 0.80 MEN1 (0.42) AKR1C1ALDH1A1TSHRAKR1C3PRMT1
SCHEMBL8528509 0.80 AKR1C1 (0.47) AKR1C1ALDH1A1TSHRAKR1C3PRMT1
SCHEMBL297682 0.79 AKR1C1 (0.39) AKR1C1ALDH1A1TSHRAKR1C3PRMT1
SCHEMBL146717 0.78 AKR1C1 (0.45) AKR1C1ALDH1A1TSHRAKR1C3PRMT1
SCHEMBL10711205 0.78 AKR1C1 (0.45) AKR1C1ALDH1A1TSHRAKR1C3PRMT1
SCHEMBL4375040 0.77 L3MBTL1 (0.47) AKR1C1ALDH1A1TSHRAKR1C3PRMT1
SCHEMBL11356886 0.76 AKR1C1 (0.40) AKR1C1ALDH1A1TSHRAKR1C3PRMT1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115536497-A Synthesis method of (E) -3,5-dihydroxy-4-isopropyl stilbene 化学与精细化工广东省实验室 2022-12-30 CN claimed
CN-115073907-A Resin composition, compound, prepreg, electric copper clad laminate, and preparation method and application thereof 成都科宜高分子科技有限公司 2022-09-20 CN claimed
EP-1248774-A2 POLYHYDROXYSTILBENES AND STILBENE OXIDES AS ANTIPSORIATIC AGENTS AND PROTEIN KINASE INHIBITORS Welichem Biotech Inc. (CA) 2002-10-16 EP claimed
WO-2001042231-A2 POLYHYDROXYSTILBENES AND STILBENE OXIDES AS ANTISORIATIC AGENTS AND PROTEIN KINASE INHIBITORS WELICHEM BIOTECH INC. (CA) 2001-06-14 WO claimed
CN-115073907-B Resin composition, compound, prepreg, electric copper-clad plate and preparation method and application thereof 成都科宜高分子科技有限公司 2024-10-25 CN disclosed
CN-111511357-B Process for preparing tazicar 德玛万科学有限责任公司 2024-04-09 CN disclosed
CN-115536497-A Synthesis method of (E) -3,5-dihydroxy-4-isopropyl stilbene 化学与精细化工广东省实验室 2022-12-30 CN disclosed
CN-115536497-A Synthesis method of (E) -3,5-dihydroxy-4-isopropyl stilbene 化学与精细化工广东省实验室 2022-12-30 CN disclosed
CN-115073907-A Resin composition, compound, prepreg, electric copper clad laminate, and preparation method and application thereof 成都科宜高分子科技有限公司 2022-09-20 CN disclosed
WO-2010148177-A2 COMPOUNDS, COMPOSITIONS, METHODS OF SYNTHESIS, AND METHODS OF TREATMENT THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) 2010-12-23 WO disclosed