SCHEMBL4632474

SCHEMBL4632474

OC(C(=Cc1ccccc1)c1ccccc1)c1ccccc1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 4/20 0.48
CES2 O00748 1/20 0.48
CES1 P23141 1/20 0.48
MAPK1 P28482 2/20 0.43
AKR1C1 Q04828 1/20 0.42
MAPT P10636 2/20 0.42
NPC1 O15118 1/20 0.42
RAB9A P51151 1/20 0.42
PRMT1 Q99873 1/20 0.39
ESR1 P03372 1/20 0.38
CYP19A1 P11511 1/20 0.37
CYP11B2 P19099 1/20 0.37
HPGD P15428 2/20 0.37
ALDH1A1 P00352 2/20 0.37
KDM4E B2RXH2 1/20 0.37
MEN1 O00255 1/20 0.37
POLB P06746 1/20 0.37
HTT P42858 1/20 0.37
KMT2A Q03164 1/20 0.37
TDP1 Q9NUW8 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6227960 1.00 LMNA (0.48) LMNACES2CES1MAPK1AKR1C1
SCHEMBL4375040 0.82 L3MBTL1 (0.47) LMNACES2CES1MAPK1AKR1C1
SCHEMBL8528509 0.81 AKR1C1 (0.47) LMNAMAPK1AKR1C1MAPTPRMT1
SCHEMBL146717 0.75 AKR1C1 (0.45) LMNAMAPK1AKR1C1MAPTPRMT1
SCHEMBL19732123 0.75 NPC1 (0.51) LMNACES2CES1MAPK1MAPT
SCHEMBL10711205 0.75 AKR1C1 (0.45) LMNAMAPK1AKR1C1MAPTPRMT1
SCHEMBL2835097 0.75 AKR1C1 (0.45) LMNAMAPK1AKR1C1MAPTPRMT1
SCHEMBL5960470 0.75 AKR1C1 (0.45) LMNAMAPK1AKR1C1MAPTPRMT1
SCHEMBL28860739 0.74 SRC (0.55) LMNAMAPK1AKR1C1MAPTPRMT1
SCHEMBL10677749 0.73 LMNA (0.46) LMNACES2CES1MAPK1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1927889-B1 Lithographic printing plate precursor FUJIFILM CORP (JP) 2014-06-25 EP disclosed
EP-1927889-A1 Lithographic printing plate precursor FUJIFILM Corporation (JP) 2008-06-04 EP disclosed
EP-1091253-B1 Plate making process for planographic plate, automatic developing apparatus and recording medium FUJI PHOTO FILM CO LTD (JP) 2005-03-30 EP disclosed
US-6558873-B1 Interlayer containing a compound capable of forming a complex with aluminum and a photopolymerizable photosensitive layer containing a photopolymerization initiator, an addition polymerizable compound capable of complexing with aluminum FUJI PHOTO FILM CO., LTD. (JP) 2003-05-06 US disclosed
EP-1091253-A2 Plate making process for planographic plate, automatic developing apparatus and recording medium FUJI PHOTO FILM CO., LTD. (JP) 2001-04-11 EP disclosed
EP-1091251-A2 Lithographic printing plate precursor FUJI PHOTO FILM CO., LTD. (JP) 2001-04-11 EP disclosed
US-6191184-B1 SUITABLE FOR FORMATION OF LIQUID CRYSTAL DISPLAY (LCD) SPACERS OR PROTECTIVE LAYERS; PHOTOSETTING PROPERTIES ADHESIVENESS TO SUBSTRATES; MECHANICAL CHARACTERISTICS, STORAGE STABILITY SHOW EXCELLENT WORKING FUJI PHOTO FILM CO., LTD. (JP) 2001-02-20 US disclosed
US-4687727-A Light-sensitive planographic printing plate with layer of diazo resin containing photopolymerizable composition FUJI PHOTO FILM CO., LTD. (JP) 1987-08-18 US disclosed
US-4511645-A ALLYL METHACRYLATE-METHACRYLIC ACID COPOLYMER, CURING AGENT, PHOTOINITIATOR FUJI PHOTO FILM CO., LTD. (JP) 1985-04-16 US disclosed
EP-0104863-A2 Light-sensitive planographic printing plate FUJI PHOTO FILM CO., LTD. (JP) 1984-04-04 EP disclosed