Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AAK1 | Q2M2I8 | 2/20 | 0.34 |
| ▸ | BCHE | P06276 | 2/20 | 0.34 |
| ▸ | ACHE | P22303 | 2/20 | 0.34 |
| ▸ | HTR5A | P47898 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL439299 | 0.79 | BCHE (0.34) | BCHEACHE | |
| SCHEMBL2712583 | 0.79 | BCHE (0.39) | AAK1BCHEACHEHTR5A | |
| SCHEMBL442311 | 0.73 | KDM4E (0.40) | BCHEACHE | |
| SCHEMBL435967 | 0.72 | NR4A2 (0.38) | BCHEACHE | |
| SCHEMBL438239 | 0.71 | ACHE (0.46) | BCHEACHEHTR5A | |
| SCHEMBL440416 | 0.71 | CDK8 (0.33) | — | |
| SCHEMBL4758327 | 0.70 | AAK1 (0.40) | AAK1 | |
| SCHEMBL29622975 | 0.70 | AAK1 (0.40) | AAK1 | |
| SCHEMBL22304448 | 0.70 | JAK2 (0.34) | AAK1 | |
| SCHEMBL2778073 | 0.68 | MAP4K4 (0.45) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120065166-A1 | Bone Modulators And Methods Therewith | ESPINA VIRGINIA (US) | 2012-03-15 | — | — | US | disclosed |