Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 4/20 | 0.46 |
| ▸ | GRM5 | P41594 | 7/20 | 0.42 |
| ▸ | FERMT2 | Q96AC1 | 1/20 | 0.39 |
| ▸ | ABL1 | P00519 | 1/20 | 0.37 |
| ▸ | BCHE | P06276 | 2/20 | 0.36 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.36 |
| ▸ | GRIN2A | Q12879 | 2/20 | 0.36 |
| ▸ | HTR5A | P47898 | 1/20 | 0.36 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.36 |
| ▸ | SOS2 | Q07890 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL439645 | 0.86 | ACHE (0.46) | ACHEBCHEGRIN1GRIN2AHTR5A | |
| SCHEMBL9377343 | 0.81 | ACHE (0.45) | ACHEGRM5FERMT2 | |
| SCHEMBL438932 | 0.79 | ACHE (0.46) | ACHEBCHEGRIN1GRIN2ANR4A2 | |
| SCHEMBL442268 | 0.79 | ACHE (0.46) | ACHEBCHEGRIN1GRIN2A | |
| SCHEMBL439004 | 0.79 | ACHE (0.43) | ACHEGRM5FERMT2 | |
| SCHEMBL438632 | 0.78 | PARP1 (0.45) | — | |
| SCHEMBL436602 | 0.75 | ACHE (0.44) | ACHENR4A2SOS2 | |
| SCHEMBL440277 | 0.75 | ACHE (0.50) | ACHEFERMT2BCHE | |
| SCHEMBL442249 | 0.74 | NPC1 (0.41) | — | |
| SCHEMBL438745 | 0.73 | KEAP1 (0.49) | ACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120065166-A1 | Bone Modulators And Methods Therewith | ESPINA VIRGINIA (US) | 2012-03-15 | — | — | US | disclosed |