Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR4A2 | P43354 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.34 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.34 |
| ▸ | BCHE | P06276 | 4/20 | 0.34 |
| ▸ | ACHE | P22303 | 4/20 | 0.34 |
| ▸ | GRIN1 | Q05586 | 3/20 | 0.33 |
| ▸ | GRIN2A | Q12879 | 3/20 | 0.33 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.32 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.32 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.32 |
| ▸ | SRC | P12931 | 1/20 | 0.32 |
| ▸ | PLAU | P00749 | 1/20 | 0.32 |
| ▸ | SOS2 | Q07890 | 1/20 | 0.32 |
| ▸ | AURKA | O14965 | 1/20 | 0.31 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL438230 | 0.83 | NR4A2 (0.35) | NR4A2SCN2ABCHEACHEADORA3 | |
| SCHEMBL22304001 | 0.80 | SCN2A (0.36) | NR4A2ALDH1A1SCN2ABCHEACHE | |
| SCHEMBL440378 | 0.78 | HAVCR2 (0.49) | ALDH1A1CYP3A4TSHRHSD17B10GRIN1 | |
| SCHEMBL441681 | 0.72 | NOS3 (0.38) | ALDH1A1BCHEACHE | |
| SCHEMBL437520 | 0.72 | AAK1 (0.34) | BCHEACHE | |
| SCHEMBL18583152 | 0.71 | ALDH1A1 (0.37) | ALDH1A1CYP3A4ADORA3ADORA1AURKA | |
| SCHEMBL440854 | 0.70 | AURKA (0.57) | ALDH1A1AURKAAURKB | |
| SCHEMBL15840581 | 0.70 | NR4A2 (0.34) | NR4A2AURKAAURKB | |
| SCHEMBL440869 | 0.68 | BCHE (0.46) | NR4A2ALDH1A1CYP3A4TSHRSCN2A | |
| SCHEMBL25481904 | 0.67 | PDE4A (0.42) | NR4A2ALDH1A1CYP3A4TSHRRECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120065166-A1 | Bone Modulators And Methods Therewith | ESPINA VIRGINIA (US) | 2012-03-15 | — | — | US | disclosed |