SCHEMBL4375432

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL4389282	0.89	APP (0.59)	APPEGFRCDK1
	SCHEMBL4381117	0.89	APP (0.57)	APPEGFRADORA2AADORA1HDAC3
	SCHEMBL4376349	0.84	APP (0.52)	APPEGFRCDK1
	SCHEMBL4377159	0.79	APP (0.47)	APPEGFRCDK1
	SCHEMBL4386606	0.78	DHFR (0.56)	—
	SCHEMBL4377998	0.78	LTA4H (0.50)	VNN1
	SCHEMBL4374715	0.76	APP (0.55)	APPEGFRAURKARPS6KB1CNR1
	SCHEMBL1090702	0.76	APP (0.51)	APPEGFRCDK1
	SCHEMBL4376506	0.74	MEN1 (0.44)	ADORA2AADORA1KDM4E
	SCHEMBL17035546	0.72	TLR8 (0.62)	—

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.