Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCHR1 | Q99705 | 18/20 | 0.43 |
| ▸ | NOS3 | P29474 | 1/20 | 0.42 |
| ▸ | NOS1 | P29475 | 1/20 | 0.42 |
| ▸ | NOS2 | P35228 | 1/20 | 0.42 |
| ▸ | ASIC3 | Q9UHC3 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL437548 | 0.77 | MCHR1 (0.49) | MCHR1NOS3NOS1NOS2ASIC3 | |
| SCHEMBL440305 | 0.77 | MCHR1 (0.58) | MCHR1ASIC3 | |
| SCHEMBL438576 | 0.76 | MCHR1 (0.49) | MCHR1NOS3NOS1NOS2ASIC3 | |
| SCHEMBL440057 | 0.76 | NOS2 (0.42) | MCHR1NOS3NOS1NOS2ASIC3 | |
| SCHEMBL4264863 | 0.73 | MCHR1 (0.56) | MCHR1ASIC3 | |
| SCHEMBL437498 | 0.73 | NOS2 (0.50) | MCHR1NOS3NOS1NOS2ASIC3 | |
| SCHEMBL440069 | 0.72 | NOS2 (0.41) | MCHR1NOS3NOS1NOS2ASIC3 | |
| SCHEMBL440237 | 0.72 | ACHE (0.59) | — | |
| SCHEMBL441586 | 0.71 | KDM4E (0.60) | MCHR1ASIC3 | |
| SCHEMBL439615 | 0.71 | NR4A2 (0.59) | MCHR1ASIC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120065166-A1 | Bone Modulators And Methods Therewith | ESPINA VIRGINIA (US) | 2012-03-15 | — | — | US | disclosed |