Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS2 | P35228 | 2/20 | 0.41 |
| ▸ | NOS3 | P29474 | 1/20 | 0.41 |
| ▸ | NOS1 | P29475 | 1/20 | 0.41 |
| ▸ | EPRS1 | P07814 | 1/20 | 0.39 |
| ▸ | MCHR1 | Q99705 | 14/20 | 0.38 |
| ▸ | BACE1 | P56817 | 1/20 | 0.36 |
| ▸ | ASIC3 | Q9UHC3 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL439885 | 0.82 | NOS3 (0.41) | NOS2NOS3NOS1MCHR1BACE1 | |
| SCHEMBL440380 | 0.81 | ALDH1A1 (0.49) | NOS2NOS3NOS1MCHR1BACE1 | |
| SCHEMBL438193 | 0.78 | NR4A2 (0.51) | EPRS1ALDH1A1 | |
| SCHEMBL437498 | 0.78 | NOS2 (0.50) | NOS2NOS3NOS1MCHR1BACE1 | |
| SCHEMBL436015 | 0.75 | NOS3 (0.39) | NOS2NOS3NOS1MCHR1BACE1 | |
| SCHEMBL438225 | 0.75 | MCHR1 (0.42) | NOS2NOS3NOS1MCHR1BACE1 | |
| SCHEMBL440057 | 0.75 | NOS2 (0.42) | NOS2NOS3NOS1MCHR1BACE1 | |
| SCHEMBL437545 | 0.73 | ADORA1 (0.55) | EPRS1ALDH1A1 | |
| SCHEMBL437548 | 0.73 | MCHR1 (0.49) | NOS2NOS3NOS1MCHR1ASIC3 | |
| SCHEMBL436520 | 0.72 | CYP2D6 (0.41) | NOS2NOS3NOS1MCHR1BACE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120065166-A1 | Bone Modulators And Methods Therewith | ESPINA VIRGINIA (US) | 2012-03-15 | — | — | US | disclosed |