Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 2/20 | 0.59 |
| ▸ | ADORA2A | P29274 | 3/20 | 0.51 |
| ▸ | ADORA1 | P30542 | 3/20 | 0.51 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.50 |
| ▸ | DHFR | P00374 | 1/20 | 0.43 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.43 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.43 |
| ▸ | CDK2 | P24941 | 1/20 | 0.43 |
| ▸ | CCNA1 | P78396 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.42 |
| ▸ | RAB9A | P51151 | 3/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.42 |
| ▸ | KDR | P35968 | 1/20 | 0.42 |
| ▸ | FLT3 | P36888 | 1/20 | 0.42 |
| ▸ | NCF1 | P14598 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL437369 | 0.78 | ACHE (0.67) | ACHEADORA2AADORA1SLC2A1SMN1; SMN2 | |
| SCHEMBL438920 | 0.77 | ACHE (0.70) | ACHEADORA2AADORA1SLC2A1SMN1; SMN2 | |
| SCHEMBL27469565 | 0.77 | ACHE (0.70) | ACHEADORA2AADORA1SMN1; SMN2RAB9A | |
| SCHEMBL2873300 | 0.76 | ACHE (1.00) | ACHEADORA2AADORA1SLC2A1SMN1; SMN2 | |
| SCHEMBL4824379 | 0.74 | ACHE (0.71) | ACHEADORA2AADORA1SMN1; SMN2RAB9A | |
| SCHEMBL437545 | 0.73 | ADORA1 (0.55) | ACHEADORA2AADORA1SLC2A1CHEK1 | |
| SCHEMBL437510 | 0.73 | RXFP1 (0.52) | ACHEADORA2AADORA1SLC2A1SMN1; SMN2 | |
| SCHEMBL439581 | 0.73 | ACHE (0.51) | ACHEADORA2AADORA1SLC2A1CHEK1 | |
| SCHEMBL28516025 | 0.73 | ACHE (0.93) | ACHEADORA2AADORA1SLC2A1SMN1; SMN2 | |
| SCHEMBL4143397 | 0.72 | ACHE (0.77) | ACHEADORA2AADORA1SMN1; SMN2RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120065166-A1 | Bone Modulators And Methods Therewith | ESPINA VIRGINIA (US) | 2012-03-15 | — | — | US | disclosed |