Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | MAOA | P21397 | 1/20 | 0.44 |
| ▸ | SYK | P43405 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | CA9 | Q16790 | 1/20 | 0.40 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.40 |
| ▸ | TUBB4A | P04350 | 2/20 | 0.37 |
| ▸ | TUBB | P07437 | 2/20 | 0.37 |
| ▸ | TUBA3C | P0DPH7 | 2/20 | 0.37 |
| ▸ | TUBA1B | P68363 | 2/20 | 0.37 |
| ▸ | TUBA4A | P68366 | 2/20 | 0.37 |
| ▸ | TUBB4B | P68371 | 2/20 | 0.37 |
| ▸ | TUBB3 | Q13509 | 2/20 | 0.37 |
| ▸ | TUBB2A | Q13885 | 2/20 | 0.37 |
| ▸ | TUBB8 | Q3ZCM7 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9834352 | 0.85 | MAOA (0.42) | SMN1; SMN2MAOAMEN1KMT2ATUBB4A | |
| SCHEMBL3979208 | 0.84 | MAOA (0.50) | SMN1; SMN2MAOASYKCA12CA1 | |
| Hydrochloric Acid SCHEMBL28215751 | 0.82 | MAOA (0.53) | SMN1; SMN2MAOACA12CA1CA2 | |
| Hydrochloric Acid SCHEMBL8708948 | 0.80 | MAOA (0.52) | MAOAGAAALDH1A1 | |
| SCHEMBL4376433 | 0.79 | HPGD (0.44) | HPGDSMN1; SMN2SYKMEN1KMT2A | |
| SCHEMBL9835970 | 0.79 | CYP17A1 (0.40) | HPGDMAOAMEN1KMT2AL3MBTL1 | |
| SCHEMBL27863553 | 0.78 | SMN1; SMN2 (0.43) | HPGDSMN1; SMN2SYKMEN1KMT2A | |
| SCHEMBL16727177 | 0.78 | HPGD (0.50) | HPGDSMN1; SMN2MEN1KMT2ACA12 | |
| SCHEMBL4688192 | 0.78 | L3MBTL1 (0.50) | SMN1; SMN2MAOAL3MBTL1MAPTALDH1A1 | |
| SCHEMBL9834103 | 0.77 | SMN1; SMN2 (0.46) | HPGDSMN1; SMN2SYKMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0208452-B1 | PYRIDINE DERIVATIVES, THEIR PRODUCTION AND USE | Takeda Chemical Industries, Ltd. (JP) | 1991-09-18 | — | — | EP | disclosed |
| US-4738975-A | Pyridine derivatives, and use as anti-ulcer agents | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1988-04-19 | — | — | US | disclosed |
| EP-0208452-A2 | Pyridine derivatives, their production and use | Takeda Chemical Industries, Ltd. (JP) | 1987-01-14 | — | — | EP | disclosed |