SCHEMBL4377344

SCHEMBL4377344

CCNc1cccc(N(C)CC)c1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HDAC4 P56524 3/20 0.48
MEF2D Q14814 3/20 0.48
CYP3A4 P08684 2/20 0.37
HTT P42858 2/20 0.37
CYP1A2 P05177 1/20 0.37
CYP2D6 P10635 1/20 0.37
MAPT P10636 1/20 0.37
CYP2C9 P11712 1/20 0.37
CYP2C19 P33261 1/20 0.37
NOS1 P29475 1/20 0.37
ALDH1A1 P00352 3/20 0.35
THRB P10828 1/20 0.35
PKM P14618 1/20 0.35
MEN1 O00255 1/20 0.34
KMT2A Q03164 1/20 0.34
GAA P10253 1/20 0.34
ALOX15 P16050 1/20 0.34
LMNA P02545 2/20 0.33
CA12 O43570 1/20 0.33
CA1 P00915 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18338708 0.85 NOS1 (0.48) HDAC4MEF2DCYP3A4HTTCYP1A2
SCHEMBL9799266 0.83 ALDH1A1 (0.53) HDAC4MEF2DCYP3A4HTTCYP1A2
SCHEMBL3363357 0.77 MAPT (0.50) CYP3A4HTTCYP1A2CYP2D6MAPT
SCHEMBL10294704 0.76 ALDH1A1 (0.44) HDAC4MEF2DHTTMAPTALDH1A1
SCHEMBL10294637 0.76 POLB (0.57) HDAC4MEF2DCYP1A2MAPTALDH1A1
SCHEMBL20057527 0.76 ALDH1A1 (0.40) HDAC4MEF2DMAPTALDH1A1MEN1
SCHEMBL11818365 0.75 CYP1A2 (0.35) HDAC4MEF2DCYP3A4HTTCYP1A2
SCHEMBL24614120 0.75 ADRA2A (0.41) HDAC4MEF2DHTTMAPTALDH1A1
SCHEMBL27389810 0.75 HDAC4 (0.46) HDAC4MEF2DMAPTALDH1A1PKM
SCHEMBL10294681 0.75 POLB (0.59) CYP3A4CYP1A2CYP2D6MAPTCYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-107011925-B Material for liquid crystal vertical alignment film, liquid crystal box prepared from material and preparation method 成都海亿科技有限公司 2020-12-29 CN claimed
CN-107011925-B Material for liquid crystal vertical alignment film, liquid crystal box prepared from material and preparation method 成都海亿科技有限公司 2020-12-29 CN disclosed
US-20170349779-A1 ANTI-WEAR AGENT DAICEL CORPORATION (JP) 2017-12-07 US disclosed
EP-3239280-A1 ANTI-WEAR AGENT Daicel Corporation (JP) 2017-11-01 EP disclosed
US-20160186617-A1 SLIDING MEMBER AND METHOD OF MANUFACTURING THE SAME TOYOTA JIDOSHA KABUSHIKI KAISHA (JP) 2016-06-30 US disclosed
EP-3037491-A1 SLIDING MEMBER AND METHOD OF MANUFACTURING THE SAME Toyota Jidosha Kabushiki Kaisha (JP) 2016-06-29 EP disclosed
US-8304469-B2 Highly heat-conductive epoxy resin composition YOKOHAMA RUBBER CO., LTD. (JP) 2012-11-06 US disclosed
US-20090298965-A1 Highly heat-conductive epoxy resin composition YOKOHAMA RUBBER CO., LTD. (JP) 2009-12-03 US disclosed
US-5051310-A Textured polyurethane molded articles having multiple sheet layers BASF AKTIENGESELLSCHAFT (DE) 1991-09-24 US disclosed