Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.48 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | CA12 | O43570 | 1/20 | 0.36 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | MGAM | O43451 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | SI | P14410 | 1/20 | 0.34 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.34 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.34 |
| ▸ | TET2 | Q6N021 | 1/20 | 0.33 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL437778 | 0.96 | TSHR (0.44) | TSHRLMNAKDM4EKMT2AMEN1 | |
| SCHEMBL13660496 | 0.93 | TSHR (0.41) | TSHRLMNAKDM4EKMT2AMEN1 | |
| SCHEMBL25868485 | 0.93 | TSHR (0.41) | TSHRLMNAKDM4EKMT2AMEN1 | |
| SCHEMBL12723336 | 0.93 | TSHR (0.48) | TSHRLMNAKDM4EKMT2AMEN1 | |
| SCHEMBL436742 | 0.91 | TSHR (0.47) | TSHRLMNAKDM4EKMT2ACA12 | |
| SCHEMBL437823 | 0.91 | TSHR (0.40) | TSHRLMNAKDM4EKMT2AMEN1 | |
| SCHEMBL10107130 | 0.90 | TSHR (0.43) | TSHRLMNAKDM4EKMT2AMEN1 | |
| SCHEMBL436743 | 0.90 | TSHR (0.43) | TSHRLMNAKDM4EKMT2AMEN1 | |
| SCHEMBL439695 | 0.88 | TSHR (0.52) | TSHRLMNAKDM4EKMT2AMEN1 | |
| SCHEMBL436739 | 0.86 | TSHR (0.50) | TSHRLMNAKDM4EKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 65 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1317422-A4 | SUBSTRATE WITH CONTROLLED AMINE DENSITY AND REGULAR SPACING AND METHOD FOR PREPARING THE SAME | POSCO (KR) | 2004-06-30 | — | — | EP | claimed |
| US-20030199577-A1 | Substrate with controlled amine density and regular spacing and method for preparing the same | POSTECH FOUNDATION (KR) | 2003-10-23 | — | — | US | claimed |
| EP-1317422-A1 | SUBSTRATE WITH CONTROLLED AMINE DENSITY AND REGULAR SPACING AND METHOD FOR PREPARING THE SAME | Posco (KR) | 2003-06-11 | — | — | EP | claimed |
| WO-2002020469-A1 | SUBSTRATE WITH CONTROLLED AMINE DENSITY AND REGULAR SPACING AND METHOD FOR PREPARING THE SAME | POHANG IRON & STEEL CO., LTD. (KR) | 2002-03-14 | — | — | WO | claimed |
| US-20260125410-A1 | MOLECULAR DEGRADERS OF EXTRACELLULAR PROTEINS | UNIV YALE (US) | 2026-05-07 | — | — | US | disclosed |
| US-20250388614-A1 | MOLECULAR DEGRADERS OF EXTRACELLULAR PROTEINS | UNIV YALE (US) | 2025-12-25 | — | — | US | disclosed |
| EP-4658263-A2 | COMPOUNDS AND METHODS FOR TREATING, AMELIORATING, OR PREVENTING ARTHRITIS | Yale University (US) | 2025-12-10 | — | — | EP | disclosed |
| US-20250161460-A1 | MOLECULAR DEGRADERS OF EXTRACELLULAR PROTEINS | UNIV YALE (US) | 2025-05-22 | — | — | US | disclosed |
| US-12234256-B2 | Molecular degraders of extracellular proteins | YALE UNIVERSITY (US) | 2025-02-25 | — | — | US | disclosed |
| US-20240382611-A1 | PEPTIDE-CONTAINING LINKERS FOR ANTIBODY-DRUG CONJUGATES | MERSANA THERAPEUTICS, INC. | 2024-11-21 | — | — | US | disclosed |
| US-12128105-B2 | Molecular degraders of extracellular proteins | YALE UNIVERSITY (US) | 2024-10-29 | — | — | US | disclosed |
| WO-2024163610-A2 | COMPOUNDS AND METHODS FOR TREATING, AMELIORATING, OR PREVENTING ARTHRITIS | YALE UNIVERSITY (US) | 2024-08-08 | — | — | WO | disclosed |
| US-20080113353-A1 | Cantilevers with fixed end and free end modified by dendron | POSTECH FOUNDATION (KR) | 2008-05-15 | — | — | US | disclosed |
| US-20040262585-A1 | Use of dendrimers and poly-branched molecules to enhance signal in fluorescent assay systems | GE HEALTHCARE UK LIMITED (GB) | 2004-12-30 | — | — | US | disclosed |
| EP-1317422-A4 | SUBSTRATE WITH CONTROLLED AMINE DENSITY AND REGULAR SPACING AND METHOD FOR PREPARING THE SAME | POSCO (KR) | 2004-06-30 | — | — | EP | disclosed |
| EP-1412755-A2 | USE OF DENDRIMERS AND POLY-BRANCHED MOLECULES TO ENHANCE SIGNAL IN FLUORESCENT ASSAY SYSTEMS | Amersham Biosciences UK Limited (GB) | 2004-04-28 | — | — | EP | disclosed |
| US-20030199577-A1 | Substrate with controlled amine density and regular spacing and method for preparing the same | POSTECH FOUNDATION (KR) | 2003-10-23 | — | — | US | disclosed |
| EP-1317422-A1 | SUBSTRATE WITH CONTROLLED AMINE DENSITY AND REGULAR SPACING AND METHOD FOR PREPARING THE SAME | Posco (KR) | 2003-06-11 | — | — | EP | disclosed |
| WO-2003014743-A2 | USE OF DENDRIMERS AND POLY-BRANCHED MOLECULES TO ENHANCE SIGNAL IN FLUORESCENT ASSAY SYSTEMS | AMERSHAM BIOSCIENCES UK LIMITED (GB) | 2003-02-20 | — | — | WO | disclosed |
| WO-2002020469-A1 | SUBSTRATE WITH CONTROLLED AMINE DENSITY AND REGULAR SPACING AND METHOD FOR PREPARING THE SAME | POHANG IRON & STEEL CO., LTD. (KR) | 2002-03-14 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240382611-A1 | PEPTIDE-CONTAINING LINKERS FOR ANTIBODY-DRUG CONJUGATES | CD2BP2, DNPEP, LNPEP | TSHR 1621/4885LMNA 3510/4885KDM4E 3327/4885 |
| US-20260125410-A1 | MOLECULAR DEGRADERS OF EXTRACELLULAR PROTEINS | ASGR1, COL2A1, FCGR2A | TSHR 126/4885LMNA 1409/4885KDM4E 1758/4885 |
| US-20250161460-A1 | MOLECULAR DEGRADERS OF EXTRACELLULAR PROTEINS | ASGR1, MSR1, LDLR | TSHR 478/4885LMNA 2180/4885KDM4E 3430/4885 |
| US-12128105-B2 | Molecular degraders of extracellular proteins | ASGR1, MSR1, LDLR | TSHR 478/4885LMNA 2180/4885KDM4E 3430/4885 |
| US-20030199577-A1 | Substrate with controlled amine density and regular spacing and method for preparing the same | ADRA1B, ADRA1D, CYP4Z1 | TSHR 3316/4885LMNA 3528/4885KDM4E 1525/4885 |
| US-20250388614-A1 | MOLECULAR DEGRADERS OF EXTRACELLULAR PROTEINS | ASGR1, COL2A1, LDLR | TSHR 157/4885LMNA 1275/4885KDM4E 2707/4885 |
| US-12234256-B2 | Molecular degraders of extracellular proteins | ASGR1, MSR1, LDLR | TSHR 478/4885LMNA 2180/4885KDM4E 3430/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.