Known targets — ChEMBL curated mechanism
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
The experimentally established mechanism targets of Phosphoric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB3 known ✓ | P13945 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.61 |
| ▸ | BLM | P54132 | 3/20 | 0.61 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.61 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.61 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.61 |
| ▸ | GABBR2 | O75899 | 3/20 | 0.55 |
| ▸ | GABBR1 | Q9UBS5 | 3/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.55 |
| ▸ | TSHR | P16473 | 1/20 | 0.55 |
| ▸ | THPO | P40225 | 1/20 | 0.55 |
| ▸ | FDPS | P14324 | 5/20 | 0.50 |
| ▸ | PDE3A | Q14432 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | GABRR1 | P24046 | 1/20 | 0.48 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.41 |
| ▸ | DRD3 | P35462 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Putrescine SCHEMBL2541172 | 0.92 | LMNA (0.61) | LMNABLMNFKB1CYP3A4PMP22 | |
| Diaminooctane SCHEMBL31657014 | 0.89 | LMNA (0.58) | LMNABLMNFKB1CYP3A4PMP22 | |
| Phosphoric Acid SCHEMBL14974535 | 0.89 | LMNA (0.58) | LMNABLMNFKB1CYP3A4PMP22 | |
| Phosphoric Acid SCHEMBL5382781 | 0.89 | LMNA (0.58) | LMNABLMNFKB1CYP3A4PMP22 | |
| Phosphoric Acid SCHEMBL5177945 | 0.89 | LMNA (0.58) | LMNABLMNFKB1CYP3A4PMP22 | |
| Phosphoric Acid SCHEMBL31656949 | 0.89 | LMNA (0.58) | LMNABLMNFKB1CYP3A4PMP22 | |
| Methyl Phosphonate SCHEMBL7997367 | 0.86 | GABBR2 (0.65) | LMNABLMNFKB1CYP3A4PMP22 | |
| Phosphoric Acid SCHEMBL726737 | 0.84 | — | — | |
| Phosphoric Acid SCHEMBL8649777 | 0.84 | ALDH1A1 (0.56) | LMNABLMNFKB1CYP3A4PMP22 | |
| Phosphoric Acid SCHEMBL16701801 | 0.84 | ALDH1A1 (0.56) | LMNABLMNFKB1CYP3A4PMP22 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1404762-B1 | A METHOD OF COLORING HAIR USING CATIONIC DYES | BASF SE (DE) | 2009-11-25 | — | — | EP | disclosed |
| US-7078498-B2 | Method of coloring hair using cationic dyes | CIBE SPECIALTY CHEMICALS CORPORATION (US) | 2006-07-18 | — | — | US | disclosed |
| US-6949630-B2 | Cationic reactive dyes | CIBA SPECIALTY CHEMICALS CORPORATION (US) | 2005-09-27 | — | — | US | disclosed |