SCHEMBL43789

SCHEMBL43789

CC(N)c1ccc2ccccc2c1

nearest known ligand 0.63

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
UGT2B7 P16662 1/20 0.63
HTR2A P28223 1/20 0.52
HTR2C P28335 1/20 0.52
HTR2B P41595 1/20 0.52
SLC6A2 P23975 4/20 0.49
SLC6A4 P31645 4/20 0.49
SLC6A3 Q01959 4/20 0.49
CYP2D6 P10635 3/20 0.49
CYP3A4 P08684 2/20 0.49
KCNH2 Q12809 2/20 0.49
MEN1 O00255 2/20 0.49
KMT2A Q03164 2/20 0.49
AOC3 Q16853 2/20 0.49
CYP1A2 P05177 1/20 0.49
TSHR P16473 1/20 0.49
HIF1A Q16665 1/20 0.49
ATM Q13315 1/20 0.48
MMP9 P14780 1/20 0.46
ADRA2A P08913 1/20 0.45
ADRA2B P18089 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29463254 1.00 UGT2B7 (0.63) UGT2B7HTR2AHTR2CHTR2BSLC6A2
SCHEMBL29350727 1.00 UGT2B7 (0.63) UGT2B7HTR2AHTR2CHTR2BSLC6A2
SCHEMBL29471009 1.00 UGT2B7 (0.63) UGT2B7HTR2AHTR2CHTR2BSLC6A2
SCHEMBL307143 1.00 UGT2B7 (0.63) UGT2B7HTR2AHTR2CHTR2BSLC6A2
SCHEMBL14019306 1.00 UGT2B7 (0.63) UGT2B7HTR2AHTR2CHTR2BSLC6A2
SCHEMBL25434816 1.00 UGT2B7 (0.63) UGT2B7HTR2AHTR2CHTR2BSLC6A2
SCHEMBL38429 1.00 UGT2B7 (0.63) UGT2B7HTR2AHTR2CHTR2BSLC6A2
Hydrochloric Acid SCHEMBL6417289 0.98 UGT2B7 (0.61) UGT2B7HTR2AHTR2CHTR2BSLC6A2
Ammonia Solution, Strong SCHEMBL27895021 0.98 UGT2B7 (0.61) UGT2B7HTR2AHTR2CHTR2BSLC6A2
SCHEMBL29254013 0.93 UGT2B7 (0.55) UGT2B7HTR2AHTR2CHTR2BSLC6A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 957 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12344592-B2 Methods, processes and intermediates for preparing chroman compounds LUPIN LIMITED (IN) 2025-07-01 US claimed
US-12075637-B2 Perovskite solar cell and fabrication method thereof CONTEMPORARY AMPEREX TECHNOLOGY CO., LIMITED (CN) 2024-08-27 US claimed
CN-114981253-B Process and intermediates for preparing chroman compounds and methods therefor 印度鲁宾有限公司 2024-06-18 CN claimed
CN-118084786-A Schiff base compound, preparation method and application thereof 安徽省东超科技有限公司 2024-05-28 CN claimed
CN-117859209-A Perovskite solar cell and preparation method thereof 宁德时代新能源科技股份有限公司 2024-04-09 CN claimed
EP-4300602-A1 PEROVSKITE SOLAR CELL AND PREPARATION METHOD THEREFOR Contemporary Amperex Technology Co., Limited (CN) 2024-01-03 EP claimed
US-20230403869-A1 PEROVSKITE SOLAR CELL AND FABRICATION METHOD THEREOF CONTEMPORARY AMPEREX TECHNOLOGY (HONG KONG) LIMITED (CN) 2023-12-14 US claimed
WO-2023216132-A1 PEROVSKITE SOLAR CELL AND PREPARATION METHOD THEREFOR 宁德时代新能源科技股份有限公司 2023-11-16 WO claimed
WO-2023214011-A1 ENZYMATIC METHOD FOR PREPARING (R)-3-AMINO-4-ARYL-BUTANOIC ACID DERIVATIVES ENZYMICALS AG (DE) 2023-11-09 WO claimed
EP-4273254-A1 ENZYMATIC METHOD FOR PREPARING (R)-3-AMINO-4-ARYL-BUTANOIC ACID DERIVATIVES Enzymicals AG (DE) 2023-11-08 EP claimed
WO-2004047738-A2 ARYLCYCLOPROPYLCARBOXYLIC AMIDES AS POTASSIUM CHANNEL OPENERS BRISTOL-MYERS SQUIBB COMPANY (US) 2004-06-10 WO claimed
US-20030166650-A1 Cinnamide derivatives as KCNQ potassium channel modulators BRISTOL-MYERS SQUIBB COMPANY 2003-09-04 US claimed
US-20020193636-A1 Benzaldehyde reacted with a primary amine to give an imine, which is hydrogenated with hydrogen in the presence of a catalyst and a water miscible solvent BASF AKTIENGESELLCHAFT (DE) 2002-12-19 US claimed
US-6476268-B1 Preparation of N-benzylamines BASF AKTIENGESELLSCHAFT (DE) 2002-11-05 US claimed
EP-1247799-A2 Process for the preparation of N-benzylamines BASF AKTIENGESELLSCHAFT (DE) 2002-10-09 EP claimed
EP-0731790-A1 TACHYKININ ANTAGONISTS A. MENARINI INDUSTRIE FARMACEUTICHE RIUNITE S.R.L. (IT) 1996-09-18 EP claimed
EP-0508307-B1 Optically active secondary amine compound; process for producing optically active secondary amine compound and process for producing optically active carboxylic acid by using said compound SUMITOMO CHEMICAL CO (JP) 1995-11-29 EP claimed
EP-0508307-A2 Optically active secondary amine compound; process for producing optically active secondary amine compound and process for producing optically active carboxylic acid by using said compound SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1992-10-14 EP claimed
US-5053512-A Total synthesis of 20(S) and 20(R)-camptothecin and compthothecin derivatives RESEARCH TRIANGLE INSTITUTE (US) 1991-10-01 US claimed
US-4014895-A Method for synthesis of optically active thiolactones SUMITOMO CHEMICAL COMPANY, LIMITED (JA) 1977-03-29 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030166650-A1 Cinnamide derivatives as KCNQ potassium channel modulators KCNH2, KCNH3, KCNQ1 UGT2B7 2187/4885HTR2A 1014/4885HTR2C 547/4885
US-20020193636-A1 Benzaldehyde reacted with a primary amine to give an imine, which is hydrogenated with hydrogen in the presence of a catalyst and a water miscible solvent HNMT, INMT, H1-2 UGT2B7 2913/4885HTR2A 565/4885HTR2C 562/4885
US-12344592-B2 Methods, processes and intermediates for preparing chroman compounds CASR, CALCR, RYR1 UGT2B7 1002/4885HTR2A 239/4885HTR2C 193/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.