Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | UGT2B7 | P16662 | 1/20 | 0.63 |
| ▸ | HTR2A | P28223 | 1/20 | 0.52 |
| ▸ | HTR2C | P28335 | 1/20 | 0.52 |
| ▸ | HTR2B | P41595 | 1/20 | 0.52 |
| ▸ | SLC6A2 | P23975 | 4/20 | 0.49 |
| ▸ | SLC6A4 | P31645 | 4/20 | 0.49 |
| ▸ | SLC6A3 | Q01959 | 4/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.49 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | AOC3 | Q16853 | 2/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.49 |
| ▸ | ATM | Q13315 | 1/20 | 0.48 |
| ▸ | MMP9 | P14780 | 1/20 | 0.46 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.45 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29463254 | 1.00 | UGT2B7 (0.63) | UGT2B7HTR2AHTR2CHTR2BSLC6A2 | |
| SCHEMBL29350727 | 1.00 | UGT2B7 (0.63) | UGT2B7HTR2AHTR2CHTR2BSLC6A2 | |
| SCHEMBL29471009 | 1.00 | UGT2B7 (0.63) | UGT2B7HTR2AHTR2CHTR2BSLC6A2 | |
| SCHEMBL43789 | 1.00 | UGT2B7 (0.63) | UGT2B7HTR2AHTR2CHTR2BSLC6A2 | |
| SCHEMBL14019306 | 1.00 | UGT2B7 (0.63) | UGT2B7HTR2AHTR2CHTR2BSLC6A2 | |
| SCHEMBL25434816 | 1.00 | UGT2B7 (0.63) | UGT2B7HTR2AHTR2CHTR2BSLC6A2 | |
| SCHEMBL38429 | 1.00 | UGT2B7 (0.63) | UGT2B7HTR2AHTR2CHTR2BSLC6A2 | |
| Hydrochloric Acid SCHEMBL6417289 | 0.98 | UGT2B7 (0.61) | UGT2B7HTR2AHTR2CHTR2BSLC6A2 | |
| Ammonia Solution, Strong SCHEMBL27895021 | 0.98 | UGT2B7 (0.61) | UGT2B7HTR2AHTR2CHTR2BSLC6A2 | |
| SCHEMBL29254013 | 0.93 | UGT2B7 (0.55) | UGT2B7HTR2AHTR2CHTR2BSLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 323 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4624455-A1 | PREPARATION METHOD FOR CHIRAL PYRROLE DERIVATIVE AND INTERMEDIATE THEREOF | Kangbaida (Sichuan) Biotechnology Co., Ltd. (CN) | 2025-10-01 | — | — | EP | claimed |
| US-20250276986-A1 | PREPARATION METHOD FOR CHIRAL PYRROLE DERIVATIVE AND INTERMEDIATE THEREOF | Kangbaida (Sichuan) Biotechnology Co., Ltd (CN) | 2025-09-04 | — | — | US | claimed |
| US-12344592-B2 | Methods, processes and intermediates for preparing chroman compounds | LUPIN LIMITED (IN) | 2025-07-01 | — | — | US | claimed |
| CN-114981253-B | Process and intermediates for preparing chroman compounds and methods therefor | 印度鲁宾有限公司 | 2024-06-18 | — | — | CN | claimed |
| WO-2024109801-A1 | PREPARATION METHOD FOR CHIRAL PYRROLE DERIVATIVE AND INTERMEDIATE THEREOF | 成都百裕制药股份有限公司 | 2024-05-30 | — | — | WO | claimed |
| CN-118084786-A | Schiff base compound, preparation method and application thereof | 安徽省东超科技有限公司 | 2024-05-28 | — | — | CN | claimed |
| CN-117005018-A | Bromine-based two-dimensional chiral perovskite single-crystal nano-sheet and preparation method and application thereof | 重庆邮电大学 | 2023-11-07 | — | — | CN | claimed |
| CN-114875472-B | Organic-inorganic hybrid chiral perovskite helical structure micron sheet and preparation method and application thereof | 河南大学 | 2023-11-03 | — | — | CN | claimed |
| US-11760750-B1 | Process for preparing levoketoconazole | NURAY CHEMICALS PRIVATE LIMITED (IN) | 2023-09-19 | — | — | US | claimed |
| CN-116145229-A | Chiral material with two-photon absorption characteristic and preparation method thereof | 深圳大学 | 2023-05-23 | — | — | CN | claimed |
| US-20090281176-A1 | PROCESS FOR THE SYNTHESIS OF RAMELTEON AND ITS INTERMEDIATES | TEVA PHARMACEUTICAL INDUSTRIES LTD. (IL) | 2009-11-12 | — | — | US | claimed |
| EP-2098519-A1 | Process for the synthesis of ramelteon and its intermediates | Teva Pharmaceutical Industries Ltd. (IL) | 2009-09-09 | — | — | EP | claimed |
| US-20090069581-A1 | PROCESS FOR THE SYNTHESIS OF RAMELTEON AND ITS INTERMEDIATES | TEVA PHARMACEUTICAL INDUSTRIES LTD. (IL) | 2009-03-12 | — | — | US | claimed |
| EP-1773768-A4 | PYRROLE DERIVATIVES AS PHARMACEUTICAL AGENTS | EXELIXIS INC (US) | 2008-08-06 | — | — | EP | claimed |
| US-20080125432-A1 | 5-Carboxamido Substituted Thiazole Derivatives that Interact With Ion Channels, In Particular With Ion Channels From the Kv Family | DEVGEN NV (BE) | 2008-05-29 | — | — | US | claimed |
| WO-2007138110-A2 | COMPOUNDS THAT INTERACT WITH ION CHANNELS, IN PARTICULAR WITH ION CHANNELS FROM THE KV FAMILY | DEVGEN N.V. (BE) | 2007-12-06 | — | — | WO | claimed |
| EP-1819330-A1 | 5-CARBOXAMIDO SUBSTITUED THIAZOLE DERIVATIVES THAT INTERACT WITH ION CHANNELS, IN PARTICULAR WITH ION CHANNELS FROM THE KV FAMILY | Devgen N.V. (BE) | 2007-08-22 | — | — | EP | claimed |
| EP-1773768-A2 | PYRROLE DERIVATIVES AS PHARMACEUTICAL AGENTS | Exelixis, Inc. (US) | 2007-04-18 | — | — | EP | claimed |
| WO-2006058905-A1 | 5-CARBOXAMIDO SUBSTITUTED THIAZOLE DERIVATIVES THAT INTERACT WITH ION CHANNELS, IN PARTICULAR WITH ION CHANNELS FROM THE Kv FAMILY | DEVGEN NV (BE) | 2006-06-08 | — | — | WO | claimed |
| WO-2006012642-A2 | PYRROLE DERIVATIVES AS PHARMACEUTICAL AGENTS | EXELIXIS, INC. (US) | 2006-02-02 | — | — | WO | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090281176-A1 | PROCESS FOR THE SYNTHESIS OF RAMELTEON AND ITS INTERMEDIATES | CYP2B6, UGT1A6, CYP2A6 | UGT2B7 35/4885HTR2A 2660/4885HTR2C 3006/4885 |
| US-20250276986-A1 | PREPARATION METHOD FOR CHIRAL PYRROLE DERIVATIVE AND INTERMEDIATE THEREOF | PIN1, DHPS, PPOX | UGT2B7 462/4885HTR2A 3309/4885HTR2C 3092/4885 |
| US-20090069581-A1 | PROCESS FOR THE SYNTHESIS OF RAMELTEON AND ITS INTERMEDIATES | CYP2B6, UGT1A6, CYP2A6 | UGT2B7 51/4885HTR2A 2028/4885HTR2C 2244/4885 |
| US-12344592-B2 | Methods, processes and intermediates for preparing chroman compounds | CASR, CALCR, RYR1 | UGT2B7 1002/4885HTR2A 239/4885HTR2C 193/4885 |
| US-20080125432-A1 | 5-Carboxamido Substituted Thiazole Derivatives that Interact With Ion Channels, In Particular With Ion Channels From the Kv Family | KCNA5, KCNA1, KCNJ2 | UGT2B7 960/4885HTR2A 695/4885HTR2C 435/4885 |
| US-11760750-B1 | Process for preparing levoketoconazole | KHK, KYAT3, PLK3 | UGT2B7 276/4885HTR2A 3991/4885HTR2C 3137/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.