Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | UGT2B7 | P16662 | 1/20 | 0.63 |
| ▸ | HTR2A | P28223 | 1/20 | 0.52 |
| ▸ | HTR2C | P28335 | 1/20 | 0.52 |
| ▸ | HTR2B | P41595 | 1/20 | 0.52 |
| ▸ | SLC6A2 | P23975 | 4/20 | 0.49 |
| ▸ | SLC6A4 | P31645 | 4/20 | 0.49 |
| ▸ | SLC6A3 | Q01959 | 4/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.49 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | AOC3 | Q16853 | 2/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.49 |
| ▸ | ATM | Q13315 | 1/20 | 0.48 |
| ▸ | MMP9 | P14780 | 1/20 | 0.46 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.45 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29463254 | 1.00 | UGT2B7 (0.63) | UGT2B7HTR2AHTR2CHTR2BSLC6A2 | |
| SCHEMBL29350727 | 1.00 | UGT2B7 (0.63) | UGT2B7HTR2AHTR2CHTR2BSLC6A2 | |
| SCHEMBL29471009 | 1.00 | UGT2B7 (0.63) | UGT2B7HTR2AHTR2CHTR2BSLC6A2 | |
| SCHEMBL43789 | 1.00 | UGT2B7 (0.63) | UGT2B7HTR2AHTR2CHTR2BSLC6A2 | |
| SCHEMBL307143 | 1.00 | UGT2B7 (0.63) | UGT2B7HTR2AHTR2CHTR2BSLC6A2 | |
| SCHEMBL14019306 | 1.00 | UGT2B7 (0.63) | UGT2B7HTR2AHTR2CHTR2BSLC6A2 | |
| SCHEMBL25434816 | 1.00 | UGT2B7 (0.63) | UGT2B7HTR2AHTR2CHTR2BSLC6A2 | |
| Hydrochloric Acid SCHEMBL6417289 | 0.98 | UGT2B7 (0.61) | UGT2B7HTR2AHTR2CHTR2BSLC6A2 | |
| Ammonia Solution, Strong SCHEMBL27895021 | 0.98 | UGT2B7 (0.61) | UGT2B7HTR2AHTR2CHTR2BSLC6A2 | |
| SCHEMBL29254013 | 0.93 | UGT2B7 (0.55) | UGT2B7HTR2AHTR2CHTR2BSLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 383 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4590663-A2 | SYNTHESIS OF CYCLOPROPANE CARBOXYLIC ACIDS | Takeda Pharmaceutical Company Limited (JP) | 2025-07-30 | — | — | EP | claimed |
| US-12104106-B2 | Compositions of chiral molecules and perovskite nanocrystals and methods of making the same | ALLIANCE FOR SUSTAINABLE ENERGY, LLC (US) | 2024-10-01 | — | — | US | claimed |
| CN-118084786-A | Schiff base compound, preparation method and application thereof | 安徽省东超科技有限公司 | 2024-05-28 | — | — | CN | claimed |
| WO-2024064214-A2 | SYNTHESIS OF CYCLOPROPANE CARBOXYLIC ACIDS | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2024-03-28 | — | — | WO | claimed |
| CN-117005018-A | Bromine-based two-dimensional chiral perovskite single-crystal nano-sheet and preparation method and application thereof | 重庆邮电大学 | 2023-11-07 | — | — | CN | claimed |
| CN-114875472-B | Organic-inorganic hybrid chiral perovskite helical structure micron sheet and preparation method and application thereof | 河南大学 | 2023-11-03 | — | — | CN | claimed |
| EP-4247380-A1 | METHODS OF SYNTHESIZING SUBSTITUTED PYRIDINONE-PYRIDINYL COMPOUNDS | Aclaris Therapeutics, Inc. (US) | 2023-09-27 | — | — | EP | claimed |
| US-11767309-B2 | Methods of synthesizing substituted pyridinone-pyridinyl compounds | ACLARIS THERAPEUTICS, INC. (US) | 2023-09-26 | — | — | US | claimed |
| US-11760750-B1 | Process for preparing levoketoconazole | NURAY CHEMICALS PRIVATE LIMITED (IN) | 2023-09-19 | — | — | US | claimed |
| CN-116685322-A | Method for synthesizing substituted pyridone-pyridyl compounds | 阿克拉瑞斯治疗股份有限公司 | 2023-09-01 | — | — | CN | claimed |
| US-20080125432-A1 | 5-Carboxamido Substituted Thiazole Derivatives that Interact With Ion Channels, In Particular With Ion Channels From the Kv Family | DEVGEN NV (BE) | 2008-05-29 | — | — | US | claimed |
| US-20080090905-A1 | Amine Salts Of (-)-2-((2-(4-Hydroxyphenyl)Ethyl)Thio)-3-(4-(2-(4-((Methylsulfonyl)Oxy)Phenoxy)Ethyl)Phenyl) Propanoic Acid | SNAPE EVAN W | 2008-04-17 | — | — | US | claimed |
| US-20080039442-A1 | Compounds With Kv4 Ion Channel Activity | DEVGEN NV (BE) | 2008-02-14 | — | — | US | claimed |
| CN-101080385-A | Amine salts of (-)-2-((2-(4-hydroxyphenyl)ethyl)thio)-3-(4-(2-(4-((methylsulfonyl)oxy)phenoxy)ethyl)phenyl)propanoic acid | ASTRAZENECA AB (SE) | 2007-11-28 | — | — | CN | claimed |
| EP-1838690-A2 | COMPOUNDS WITH KV4 ION CHANNEL ACTIVITY | Devgen N.V. (BE) | 2007-10-03 | — | — | EP | claimed |
| EP-1819330-A1 | 5-CARBOXAMIDO SUBSTITUED THIAZOLE DERIVATIVES THAT INTERACT WITH ION CHANNELS, IN PARTICULAR WITH ION CHANNELS FROM THE KV FAMILY | Devgen N.V. (BE) | 2007-08-22 | — | — | EP | claimed |
| WO-2007038277-A2 | RESOLUTION OF ALPHA-(PHENOXY) PHENYLACETIC ACID DERIVATIVES WITH NAPHTHYL-ALKYLAMINES | METABOLEX, INC. (US) | 2007-04-05 | — | — | WO | claimed |
| US-20070073082-A1 | Reacting enantiomers of 4-chloro- alpha -(3-trifluoromethylphenoxy)phenylacetic acid with (S)-(-)-1-(2-naphthyl)ethylamine to form an ammonium salt; separating the naphthylalkylammonium salt of the first enantiomer from the mixture; separating naphthylalkylamine | METABOLEX, INC. (US) | 2007-03-29 | — | — | US | claimed |
| WO-2006066879-A2 | COMPOUNDS WITH KV4 ION CHANNEL ACTIVITY | DEVGEN N.V. (BE) | 2006-06-29 | — | — | WO | claimed |
| WO-2006058905-A1 | 5-CARBOXAMIDO SUBSTITUTED THIAZOLE DERIVATIVES THAT INTERACT WITH ION CHANNELS, IN PARTICULAR WITH ION CHANNELS FROM THE Kv FAMILY | DEVGEN NV (BE) | 2006-06-08 | — | — | WO | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080090905-A1 | Amine Salts Of (-)-2-((2-(4-Hydroxyphenyl)Ethyl)Thio)-3-(4-(2-(4-((Methylsulfonyl)Oxy)Phenoxy)Ethyl)Phenyl) Propanoic Acid | GPR119, CPT1B, PNLIP | UGT2B7 1607/4885HTR2A 396/4885HTR2C 1201/4885 |
| US-11767309-B2 | Methods of synthesizing substituted pyridinone-pyridinyl compounds | PIR, PUM1, ZRANB2 | UGT2B7 1988/4885HTR2A 1583/4885HTR2C 2767/4885 |
| US-20070073082-A1 | Reacting enantiomers of 4-chloro- alpha -(3-trifluoromethylphenoxy)phenylacetic acid with (S)-(-)-1-(2-naphthyl)ethylamine to form an ammonium salt; separating the naphthylalkylammonium salt of the first enantiomer from the mixture; separating naphthylalkylamine | NAT1, SLC43A1, AGTR1 | UGT2B7 1900/4885HTR2A 304/4885HTR2C 249/4885 |
| US-20080039442-A1 | Compounds With Kv4 Ion Channel Activity | KCNA4, HCN4, KCNN4 | UGT2B7 780/4885HTR2A 2253/4885HTR2C 2278/4885 |
| US-20080125432-A1 | 5-Carboxamido Substituted Thiazole Derivatives that Interact With Ion Channels, In Particular With Ion Channels From the Kv Family | KCNA5, KCNA1, KCNJ2 | UGT2B7 960/4885HTR2A 695/4885HTR2C 435/4885 |
| US-11760750-B1 | Process for preparing levoketoconazole | KHK, KYAT3, PLK3 | UGT2B7 276/4885HTR2A 3991/4885HTR2C 3137/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.