SCHEMBL4378900

SCHEMBL4378900

C=CCOc1c(Br)cc(CCC)cc1Br

nearest known ligand 0.52

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
LMNA P02545 3/20 0.46
SMN1; SMN2 Q16637 1/20 0.46
THRB P10828 6/20 0.42
THRA P10827 5/20 0.42
KMT2A Q03164 4/20 0.42
MEN1 O00255 3/20 0.42
MAPT P10636 3/20 0.42
L3MBTL1 Q9Y468 2/20 0.42
NPSR1 Q6W5P4 1/20 0.42
ALDH1A1 P00352 2/20 0.41
HRH3 Q9Y5N1 1/20 0.41
HPGD P15428 1/20 0.41
GAA P10253 2/20 0.40
HTT P42858 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10712071 0.86 HRH3 (0.44) LMNASMN1; SMN2THRBTHRAKMT2A
SCHEMBL7598077 0.82 LMNA (0.43) LMNASMN1; SMN2THRBKMT2AMEN1
SCHEMBL5090067 0.81 THRA (0.42) LMNASMN1; SMN2THRBTHRAKMT2A
SCHEMBL28048089 0.80 THRB (0.42) LMNASMN1; SMN2THRBTHRAKMT2A
SCHEMBL6578128 0.78 LMNA (0.47) LMNASMN1; SMN2KMT2AMEN1MAPT
SCHEMBL42433 0.77 LMNA (0.45) LMNASMN1; SMN2KMT2AMEN1MAPT
SCHEMBL7600877 0.77 LMNA (0.45) LMNASMN1; SMN2THRBKMT2AMEN1
SCHEMBL22639058 0.75 HRH3 (0.51) SMN1; SMN2THRBTHRAMAPTL3MBTL1
SCHEMBL6364273 0.75 LMNA (0.45) LMNASMN1; SMN2THRBTHRAKMT2A
SCHEMBL9848685 0.74 THRB (0.51) THRBTHRAALDH1A1HRH3HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-104592662-A High-thermal-resistance expandable polystyrene (EPS) composition particles and preparation method thereof BEIJING SITANLI TECHNOLOGY CO LTD 2015-05-06 CN claimed
EP-1448612-A1 VINYLAROMATIC POLYMERS WITH IMPROVED FLAME RESISTANCE Polimeri Europa S.p.A. (IT) 2004-08-25 EP claimed
WO-2003046016-A1 VINYLAROMATIC POLYMERS WITH IMPROVED FLAME RESISTANCE POLIMERI EUROPA S.P.A. (IT) 2003-06-05 WO claimed
JP-57038831-A None JP disclosed
CN-113966359-A Additive composition 株式会社艾迪科 2022-01-21 CN disclosed
CN-112739765-A Flame-retardant resin composition and molded article 出光狮王塑料株式会社 2021-04-30 CN disclosed
CN-112739764-A Flame-retardant resin composition and molded article 出光狮王塑料株式会社 2021-04-30 CN disclosed
WO-2021020020-A1 ADDITIVE COMPOSITION 株式会社ADEKA 2021-02-04 WO disclosed
WO-2020067205-A1 FLAME-RETARDANT RESIN COMPOSITION AND MOLDED OBJECT 出光ライオンコンポジット株式会社 2020-04-02 WO disclosed
WO-2020067207-A1 FLAME-RETARDANT RESIN COMPOSITION AND MOLDED BODY 出光ライオンコンポジット株式会社 2020-04-02 WO disclosed
CN-105637022-A Composite resin pre-expanded particles containing carbon black and method for producing same, and expanded molded article SEKISUI PLASTICS 2016-06-01 CN disclosed
CN-101353439-B Method of producing expandable polystyrene beads which have excellent heat insulation properties KOREA KUMHO PETROCHEM CO LTD 2012-09-05 CN disclosed
WO-2009014279-A1 METHOD FOR PRODUCING EXPANDABLE POLYSTYRENE BEADS WHICH HAVE EXCELLENT HEAT INSULATION PROPERTIES KOREA KUMHO PETROCHEMICAL CO., LTD (KR) 2009-01-29 WO disclosed
CN-101353439-A Method of producing expandable polystyrene beads which have excellent heat insulation properties KOREA KUMHO PETROCHEM CO LTD (KR) 2009-01-28 CN disclosed
EP-1448612-A1 VINYLAROMATIC POLYMERS WITH IMPROVED FLAME RESISTANCE Polimeri Europa S.p.A. (IT) 2004-08-25 EP disclosed
WO-2003046016-A1 VINYLAROMATIC POLYMERS WITH IMPROVED FLAME RESISTANCE POLIMERI EUROPA S.P.A. (IT) 2003-06-05 WO disclosed
JP-S5738831-A PRODUCTION OF FLAME-RETARDING POLYSTYRENE RESIN FOAM SEKISUI PLASTICS CO LTD 1982-03-03 JP disclosed
EP-0032993-A2 Fireproofed styrene polymers BASF Aktiengesellschaft (DE) 1981-08-05 EP disclosed
JP-S05738831-A 0001-01-01 JP disclosed