Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPM8 | Q7Z2W7 | 6/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | PGR | P06401 | 1/20 | 0.44 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.44 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.44 |
| ▸ | HTR2A | P28223 | 1/20 | 0.44 |
| ▸ | HRH1 | P35367 | 1/20 | 0.44 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.44 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.41 |
| ▸ | MLYCD | O95822 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | XBP1 | P17861 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6383907 | 0.93 | NPSR1 (0.50) | TRPM8NPSR1ALDH1A1HPGDPGR | |
| SCHEMBL6383709 | 0.93 | NPSR1 (0.50) | TRPM8NPSR1ALDH1A1HPGDPGR | |
| SCHEMBL11170030 | 0.90 | NPSR1 (0.45) | TRPM8NPSR1ALDH1A1HPGDMAPT | |
| SCHEMBL11783815 | 0.85 | TRPM8 (0.53) | TRPM8NPSR1ALDH1A1HPGDPGR | |
| SCHEMBL28452950 | 0.81 | MLYCD (0.53) | TRPM8ALDH1A1HPGDPGRADRA2A | |
| SCHEMBL8896112 | 0.80 | PARP1 (0.46) | TRPM8HPGD | |
| SCHEMBL458409 | 0.79 | NPSR1 (0.59) | TRPM8NPSR1ALDH1A1HPGDPGR | |
| SCHEMBL154606 | 0.78 | TRPM8 (0.53) | TRPM8NPSR1ALDH1A1HPGDPGR | |
| Hydrochloric Acid SCHEMBL3759428 | 0.78 | NPSR1 (0.57) | TRPM8NPSR1ALDH1A1HPGDPGR | |
| Hydrochloric Acid SCHEMBL31125741 | 0.78 | NPSR1 (0.57) | TRPM8NPSR1ALDH1A1HPGDPGR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1203763-B1 | Process for the synthesis of beta-hydroxyalkylamides | EMS CHEMIE AG (CH) | 2009-11-18 | — | — | EP | disclosed |
| US-7030272-B2 | β-hydroxyalkylamides process for their production and their use | KAPLAN ANDREAS | 2006-04-18 | — | — | US | disclosed |
| US-20040260123-A1 | Beta-hydroxyalkylamides process for their production and their use | KAPLAN ANDREAS (CH) | 2004-12-23 | — | — | US | disclosed |
| US-20020055595-A1 | Beta-hydroxyalklyamides, process for their production and their use | EMS-CHEMIE AG (CH) | 2002-05-09 | — | — | US | disclosed |
| EP-1203763-A2 | Beta-hydroxyalkylamides, their use and a process for their synthesis | EMS-Chemie AG (CH) | 2002-05-08 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020055595-A1 | Beta-hydroxyalklyamides, process for their production and their use | HACL2, CYP8B1, HDHD5 | TRPM8 4475/4885NPSR1 3857/4885ALDH1A1 62/4885 |
| US-20040260123-A1 | Beta-hydroxyalkylamides process for their production and their use | HACL2, CYP8B1, ADH1A | TRPM8 4752/4885NPSR1 3948/4885ALDH1A1 27/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.