Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Oxalic Acid SCHEMBL7991342 | 0.93 | LMNA (0.54) | ALDH1A1MEN1KMT2ATDP1TSHR | |
| SCHEMBL7988365 | 0.87 | MEN1 (0.48) | ALDH1A1MEN1KMT2ATDP1LMNA | |
| SCHEMBL4382478 | 0.85 | PPARG (0.39) | MEN1KMT2ALMNASMN1; SMN2KCNH2 | |
| SCHEMBL4380966 | 0.83 | NQO1 (0.45) | ALDH1A1MEN1KMT2ATDP1TSHR | |
| SCHEMBL4384964 | 0.83 | CYP17A1 (0.36) | MEN1KMT2ALMNASMN1; SMN2KCNH2 | |
| SCHEMBL4386689 | 0.80 | LMNA (0.45) | ALDH1A1TSHRLMNASMN1; SMN2KCNH2 | |
| SCHEMBL7987297 | 0.80 | HRH3 (0.54) | ALDH1A1MEN1KMT2ATDP1LMNA | |
| SCHEMBL7991257 | 0.78 | CYP3A4 (0.45) | ALDH1A1MEN1KMT2ALMNASMN1; SMN2 | |
| SCHEMBL7961327 | 0.77 | RAB9A (0.43) | ALDH1A1MEN1KMT2ALMNAKCNH2 | |
| SCHEMBL4392013 | 0.76 | HRH3 (0.43) | NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6248765-B1 | ANTIINFLAMMATORY AGENTS; HYPOTENSIVE AGENTS | INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICAL (FR) | 2001-06-19 | — | — | US | claimed |
| WO-1996029315-A2 | IMIDAZOLE DERIVATIVES AS HISTAMINE RECEPTOR H3 (ANT)AGONISTS | INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (FR) | 1996-09-26 | — | — | WO | claimed |
| EP-0760811-B1 | IMIDAZOLE DERIVATIVES AS HISTAMINE RECEPTOR H3 MODULATORS | INST NAT SANTE RECH MED (FR) | 2009-11-18 | — | — | EP | disclosed |
| WO-1996029315-A2 | IMIDAZOLE DERIVATIVES AS HISTAMINE RECEPTOR H3 (ANT)AGONISTS | INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (FR) | 1996-09-26 | — | — | WO | disclosed |