Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP17A1 | P05093 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | PPARG | P37231 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4382478 | 0.89 | PPARG (0.39) | KCNH2MEN1KMT2AHRH3LMNA | |
| SCHEMBL7988365 | 0.86 | MEN1 (0.48) | KCNH2MEN1KMT2AHRH3LMNA | |
| SCHEMBL4379596 | 0.83 | ALDH1A1 (0.49) | KCNH2MEN1KMT2ALMNASMN1; SMN2 | |
| SCHEMBL4379134 | 0.80 | HRH3 (0.39) | HRH3SMN1; SMN2 | |
| SCHEMBL4389358 | 0.80 | HRH3 (0.50) | KCNH2HRH3 | |
| Oxalic Acid SCHEMBL7991342 | 0.79 | LMNA (0.54) | MEN1KMT2ALMNASMN1; SMN2 | |
| SCHEMBL7987297 | 0.79 | HRH3 (0.54) | CYP2C9CYP2C19KCNH2MEN1KMT2A | |
| SCHEMBL4380966 | 0.79 | NQO1 (0.45) | CYP2C9CYP2C19KCNH2MEN1KMT2A | |
| SCHEMBL4392013 | 0.78 | HRH3 (0.43) | HRH3 | |
| SCHEMBL7976959 | 0.77 | ITGB3 (0.36) | SLC2A1KCNH2HRH3PPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6248765-B1 | ANTIINFLAMMATORY AGENTS; HYPOTENSIVE AGENTS | INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICAL (FR) | 2001-06-19 | — | — | US | claimed |
| EP-0760811-B1 | IMIDAZOLE DERIVATIVES AS HISTAMINE RECEPTOR H3 MODULATORS | INST NAT SANTE RECH MED (FR) | 2009-11-18 | — | — | EP | disclosed |