Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.62 |
| ▸ | MAPT | P10636 | 5/20 | 0.62 |
| ▸ | PKM | P14618 | 3/20 | 0.62 |
| ▸ | HTT | P42858 | 2/20 | 0.62 |
| ▸ | MYC | P01106 | 1/20 | 0.53 |
| ▸ | PLK1 | P53350 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.50 |
| ▸ | MEN1 | O00255 | 3/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | POLB | P06746 | 2/20 | 0.50 |
| ▸ | HPGD | P15428 | 2/20 | 0.50 |
| ▸ | APEX1 | P27695 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | RXRA | P19793 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL437676 | 0.86 | ALDH1A1 (0.67) | ALDH1A1MAPTPKMHTTMYC | |
| SCHEMBL10205950 | 0.84 | PLK1 (0.54) | ALDH1A1HTTPLK1LMNAMEN1 | |
| SCHEMBL14280204 | 0.84 | MAPT (0.46) | ALDH1A1MAPTPKMHTTMYC | |
| SCHEMBL14280209 | 0.83 | HTT (0.55) | ALDH1A1MAPTPKMHTTPLK1 | |
| SCHEMBL438115 | 0.80 | TDP1 (0.58) | ALDH1A1MAPTPKMMYCPLK1 | |
| SCHEMBL435621 | 0.78 | TP53 (0.52) | ALDH1A1MAPTPKMHTTMYC | |
| SCHEMBL12851588 | 0.78 | TP53 (0.63) | ALDH1A1MAPTSMN1; SMN2LMNAMEN1 | |
| SCHEMBL435644 | 0.78 | RXRA (0.58) | ALDH1A1MAPTPLK1SMN1; SMN2MEN1 | |
| SCHEMBL28147295 | 0.77 | ALDH1A1 (0.78) | ALDH1A1MAPTPKMHTTMYC | |
| SCHEMBL437666 | 0.77 | L3MBTL1 (0.49) | ALDH1A1MAPTPLK1APEX1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 65 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8217073-B2 | Pyrrole derivatives as therapeutic compounds | MYREXIS, INC. (US) | 2012-07-10 | — | — | US | claimed |
| US-20120065241-A1 | THERAPEUTIC COMPOUNDS FOR DISEASES AND DISORDERS | MYREXIS, INC. (US) | 2012-03-15 | — | — | US | claimed |
| EP-2143708-B1 | OLIGOANILINE COMPOUND | NISSAN CHEMICAL IND LTD (JP) | 2016-04-06 | — | — | EP | disclosed |
| US-8956729-B2 | Surface-treated metal material and process for producing the same | NIPPON STEEL & SUMITOMO METAL CORPORATION (JP) | 2015-02-17 | — | — | US | disclosed |
| EP-1621582-B1 | RESIN COMPOSITION AND PROCESS FOR PRODUCING THE SAME | KANEKA CORP (JP) | 2012-10-31 | — | — | EP | disclosed |
| US-8298444-B2 | Oligoaniline compound | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 2012-10-30 | — | — | US | disclosed |
| EP-1928827-B1 | PYRROLE DERIVATIVES AS THERAPEUTIC COMPOUNDS | MYRIAD GENETICS INC (US) | 2012-08-22 | — | — | EP | disclosed |
| EP-1928827-B1 | PYRROLE DERIVATIVES AS THERAPEUTIC COMPOUNDS | MYRIAD GENETICS INC (US) | 2012-08-22 | — | — | EP | disclosed |
| US-8217073-B2 | Pyrrole derivatives as therapeutic compounds | MYREXIS, INC. (US) | 2012-07-10 | — | — | US | disclosed |
| US-8217073-B2 | Pyrrole derivatives as therapeutic compounds | MYREXIS, INC. (US) | 2012-07-10 | — | — | US | disclosed |
| US-8217073-B2 | Pyrrole derivatives as therapeutic compounds | MYREXIS, INC. (US) | 2012-07-10 | — | — | US | disclosed |
| EP-0457616-B1 | Flame retardant coating compositions and coated articles | SHINETSU CHEMICAL CO (JP) | 1995-04-05 | — | — | EP | disclosed |
| EP-0308198-B1 | Thermoplastic polymethacrylimide resin composition | MITSUBISHI RAYON CO (JP) | 1994-06-22 | — | — | EP | disclosed |
| US-5283279-A | Polyorganosiloxane graft copolymer emulsion; when cured has sufficient extensibility to follow cracks in underlying surface | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 1994-02-01 | — | — | US | disclosed |
| EP-0457616-A2 | Flame retardant coating compositions and coated articles | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 1991-11-21 | — | — | EP | disclosed |
| US-4902742-A | Thermoplastic polymethacrylimide resin composition | MITSUBISHI RAYON CO., LTD. (JP) | 1990-02-20 | — | — | US | disclosed |
| EP-0308198-A2 | Thermoplastic polymethacrylimide resin composition | MITSUBISHI RAYON CO., LTD. (JP) | 1989-03-22 | — | — | EP | disclosed |
| US-4618656-A | WATER OR MOISTURE CURED GLASTOMER HAVING IMPROVED TENSILE STRENGTH | KANEGAFUCHI CHEMICAL INDUSTRY CO., LTD. (JP) | 1986-10-21 | — | — | US | disclosed |
| US-4618653-A | Novel polymer and cured product of the same | KANEGAFUCHI CHEMICAL INDUSTRY CO., LTD. (JP) | 1986-10-21 | — | — | US | disclosed |
| EP-0159715-A2 | Novel polymer and cured product of the same | Kanegafuchi Chemical Industry Co., Ltd. (JP) | 1985-10-30 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120065241-A1 | THERAPEUTIC COMPOUNDS FOR DISEASES AND DISORDERS | NLN, SLC18A2, GOLT1B | ALDH1A1 2759/4885MAPT 30/4885PKM 1366/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.