Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 3/20 | 0.45 |
| ▸ | RAB9A | P51151 | 3/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.45 |
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | GLA | P06280 | 2/20 | 0.45 |
| ▸ | GAA | P10253 | 2/20 | 0.45 |
| ▸ | HPGD | P15428 | 2/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | CASP1 | P29466 | 1/20 | 0.45 |
| ▸ | CASP7 | P55210 | 1/20 | 0.45 |
| ▸ | ATM | Q13315 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | IKBKB | O14920 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27659692 | 0.85 | L3MBTL1 (0.44) | NPC1RAB9AKMT2AALDH1A1KDM4E | |
| SCHEMBL438922 | 0.81 | KDM4E (0.53) | KMT2AALDH1A1KDM4EMAPTSMN1; SMN2 | |
| SCHEMBL7069958 | 0.80 | ALDH1A1 (0.43) | NPC1RAB9AKMT2AALDH1A1KDM4E | |
| SCHEMBL25999187 | 0.79 | ALDH1A1 (0.47) | NPC1RAB9AKMT2AALDH1A1KDM4E | |
| SCHEMBL438266 | 0.79 | KMT2A (0.47) | NPC1RAB9AKMT2AALDH1A1KDM4E | |
| SCHEMBL440854 | 0.79 | AURKA (0.57) | NPC1RAB9AKMT2AALDH1A1KDM4E | |
| SCHEMBL439457 | 0.78 | NPC1 (0.57) | NPC1RAB9AKMT2AALDH1A1KDM4E | |
| SCHEMBL25999202 | 0.78 | DPP4 (0.51) | NPC1RAB9AKMT2AALDH1A1KDM4E | |
| SCHEMBL25999208 | 0.77 | HPGD (0.51) | NPC1RAB9AKMT2AALDH1A1KDM4E | |
| SCHEMBL438198 | 0.76 | MAPK1 (0.63) | NPC1RAB9AKMT2AALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120065166-A1 | Bone Modulators And Methods Therewith | ESPINA VIRGINIA (US) | 2012-03-15 | — | — | US | disclosed |