Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.62 |
| ▸ | SIGMAR1 | Q99720 | 9/20 | 0.60 |
| ▸ | DRD4 | P21917 | 3/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.56 |
| ▸ | DRD2 | P14416 | 1/20 | 0.56 |
| ▸ | DRD3 | P35462 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.56 |
| ▸ | BCHE | P06276 | 1/20 | 0.55 |
| ▸ | ACHE | P22303 | 1/20 | 0.55 |
| ▸ | BACE1 | P56817 | 1/20 | 0.55 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | TMEM97 | Q5BJF2 | 2/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | SLC6A12 | P48065 | 1/20 | 0.53 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.53 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.53 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4388051 | 0.89 | DPP7 (0.54) | DPP7SIGMAR1DRD4KMT2AMAPK1 | |
| SCHEMBL4387958 | 0.87 | DPP7 (0.52) | DPP7SIGMAR1DRD4KMT2AMAPK1 | |
| SCHEMBL8329414 | 0.80 | SIGMAR1 (0.53) | SIGMAR1DRD3ALDH1A1BCHEACHE | |
| SCHEMBL4383295 | 0.79 | MCHR1 (0.47) | DPP7SIGMAR1DRD4KMT2ADRD2 | |
| SCHEMBL6316398 | 0.78 | SIGMAR1 (0.73) | SIGMAR1POLB | |
| SCHEMBL2425554 | 0.78 | SIGMAR1 (0.78) | DPP7SIGMAR1DRD4KMT2AMAPK1 | |
| SCHEMBL14681148 | 0.77 | SIGMAR1 (0.60) | DPP7SIGMAR1DRD4KMT2ADRD2 | |
| SCHEMBL4387949 | 0.77 | DPP7 (0.55) | DPP7SIGMAR1DRD4KMT2AMAPK1 | |
| Hydrochloric Acid SCHEMBL21410212 | 0.77 | SIGMAR1 (0.76) | DPP7SIGMAR1DRD4KMT2AMAPK1 | |
| Hydrochloric Acid SCHEMBL14674370 | 0.76 | SIGMAR1 (0.58) | DPP7SIGMAR1DRD4KMT2ADRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090181948-A1 | DIAMINE DERIVATIVE | KYOWA HAKKO KOGYO CO., LTD. (JP) | 2009-07-16 | — | — | US | disclosed |
| EP-1847530-A1 | DIAMINE DERIVATIVE | KYOWA HAKKO KOGYO CO., LTD. (JP) | 2007-10-24 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090181948-A1 | DIAMINE DERIVATIVE | ARG1, PRMT5, PRMT1 | DPP7 2407/4885SIGMAR1 984/4885DRD4 75/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.