Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.55 |
| ▸ | MBTD1 | Q05BQ5 | 2/20 | 0.47 |
| ▸ | L3MBTL3 | Q96JM7 | 2/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | DRD4 | P21917 | 4/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | DRD2 | P14416 | 2/20 | 0.45 |
| ▸ | DRD3 | P35462 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | ACHE | P22303 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4381667 | 0.79 | DPP7 (0.44) | DPP7SIGMAR1GAADRD4KMT2A | |
| SCHEMBL6212951 | 0.78 | L3MBTL3 (0.66) | MBTD1L3MBTL3L3MBTL1SIGMAR1DRD4 | |
| SCHEMBL4383023 | 0.77 | DPP7 (0.62) | DPP7SIGMAR1DRD4KMT2ADRD2 | |
| Hydrochloric Acid SCHEMBL28690097 | 0.76 | L3MBTL3 (0.64) | MBTD1L3MBTL3L3MBTL1SIGMAR1DRD4 | |
| SCHEMBL13990656 | 0.76 | L3MBTL3 (0.68) | MBTD1L3MBTL3L3MBTL1SIGMAR1DRD4 | |
| SCHEMBL8713729 | 0.74 | GAA (0.50) | SIGMAR1GAA | |
| SCHEMBL3285312 | 0.74 | DRD2 (0.65) | MBTD1L3MBTL3L3MBTL1SIGMAR1DRD4 | |
| SCHEMBL3552998 | 0.74 | SIGMAR1 (0.67) | DPP7L3MBTL1SIGMAR1DRD4KMT2A | |
| Hydrochloric Acid SCHEMBL4324912 | 0.72 | DRD2 (0.63) | MBTD1L3MBTL3L3MBTL1SIGMAR1DRD4 | |
| SCHEMBL24163317 | 0.71 | RECQL (0.69) | MBTD1L3MBTL3SIGMAR1DRD4KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090181948-A1 | DIAMINE DERIVATIVE | KYOWA HAKKO KOGYO CO., LTD. (JP) | 2009-07-16 | — | — | US | disclosed |
| EP-1847530-A1 | DIAMINE DERIVATIVE | KYOWA HAKKO KOGYO CO., LTD. (JP) | 2007-10-24 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090181948-A1 | DIAMINE DERIVATIVE | ARG1, PRMT5, PRMT1 | DPP7 2407/4885MBTD1 3597/4885L3MBTL3 1965/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.