SCHEMBL4388051

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL4387958	0.93	DPP7 (0.52)	DPP7SIGMAR1KMT2ADRD4MAPK1
	SCHEMBL4383023	0.89	DPP7 (0.62)	DPP7SIGMAR1KMT2ADRD4MAPK1
	SCHEMBL4383295	0.81	MCHR1 (0.47)	DPP7SIGMAR1KMT2ADRD4DRD2
	SCHEMBL4690024	0.76	ACHE (0.69)	DPP7SIGMAR1KMT2AALDH1A1MEN1
	SCHEMBL8329414	0.73	SIGMAR1 (0.53)	SIGMAR1ALDH1A1DRD3TMEM97MCHR1
	Methylamine SCHEMBL27725391	0.72	ACHE (0.64)	DPP7SIGMAR1KMT2AALDH1A1MEN1
	SCHEMBL6316398	0.72	SIGMAR1 (0.73)	SIGMAR1POLBL3MBTL1
	SCHEMBL2425554	0.71	SIGMAR1 (0.78)	DPP7SIGMAR1KMT2ADRD4MAPK1
	SCHEMBL694949	0.71	SIGMAR1 (0.82)	SIGMAR1KMT2ADRD4MAPK1DRD2
	SCHEMBL3075354	0.71	SIGMAR1 (0.81)	SIGMAR1POLBL3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.