Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.62 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.62 |
| ▸ | HTT | P42858 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | TACR3 | P29371 | 1/20 | 0.44 |
| ▸ | TRPV6 | Q9H1D0 | 1/20 | 0.43 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4384152 | 0.90 | ALDH1A1 (0.58) | ALDH1A1KDM4EHTTLMNAHPGD | |
| SCHEMBL4379702 | 0.78 | EGFR (0.44) | ALDH1A1KDM4EHTTLMNAHPGD | |
| SCHEMBL4386243 | 0.78 | MAPK1 (0.44) | KDM4ELMNAKMT2ATDP1 | |
| SCHEMBL4384593 | 0.78 | KMT2A (0.51) | ALDH1A1HTTLMNAHPGDMEN1 | |
| SCHEMBL4392819 | 0.78 | LMNA (0.61) | ALDH1A1HTTLMNAHPGDKMT2A | |
| SCHEMBL4386601 | 0.76 | ALDH1A1 (0.62) | ALDH1A1LMNAHPGDKMT2ATDP1 | |
| SCHEMBL4386467 | 0.76 | MAPT (0.55) | ALDH1A1KDM4EHTTMEN1KMT2A | |
| SCHEMBL4386854 | 0.76 | TACR3 (0.52) | ALDH1A1KDM4EMEN1KMT2ATACR3 | |
| SCHEMBL27781452 | 0.73 | KDM4E (0.69) | ALDH1A1KDM4EHTTLMNATDP1 | |
| SCHEMBL4382807 | 0.73 | KDM4E (0.55) | ALDH1A1KDM4EMEN1KMT2ATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7538241-B2 | Hsp90 family protein inhibitors | KYOWA HAKKO KOGYO CO., LTD. (JP) | 2009-05-26 | — | — | US | disclosed |
| US-20070155813-A1 | Hsp90 family protein inhibitors | KYOWA HAKKO KOGYO CO., LTD. (JP) | 2007-07-05 | — | — | US | disclosed |
| EP-1704856-A1 | HSP90 FAMILY PROTEIN INHIBITOR | KYOWA HAKKO KOGYO CO., LTD. (JP) | 2006-09-27 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070155813-A1 | Hsp90 family protein inhibitors | HSP90AB1, HEATR1, HSP90AB2P | ALDH1A1 3520/4885KDM4E 3223/4885HTT 538/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.