Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 4/20 | 0.49 |
| ▸ | ITGA2B | P08514 | 4/20 | 0.49 |
| ▸ | LTA4H | P09960 | 1/20 | 0.47 |
| ▸ | CPB2 | Q96IY4 | 3/20 | 0.47 |
| ▸ | EPOR | P19235 | 2/20 | 0.46 |
| ▸ | ECE1 | P42892 | 1/20 | 0.45 |
| ▸ | CPB1 | P15086 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.44 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.43 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.43 |
| ▸ | SIRT3 | Q9NTG7 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7166074 | 1.00 | ITGB3 (0.49) | ITGB3ITGA2BLTA4HCPB2EPOR | |
| SCHEMBL5241716 | 0.98 | LTA4H (0.48) | ITGB3ITGA2BLTA4HCPB2EPOR | |
| SCHEMBL11588837 | 0.94 | ALDH1A1 (0.47) | ITGB3ITGA2BLTA4HEPORALDH1A1 | |
| SCHEMBL8643591 | 0.87 | ALDH1A1 (0.50) | ALDH1A1MAPK1L3MBTL1SLC6A2SLC6A3 | |
| SCHEMBL5242448 | 0.87 | ALDH1A1 (0.50) | ALDH1A1MAPK1L3MBTL1SLC6A2SLC6A3 | |
| SCHEMBL34463650 | 0.85 | LTA4H (0.47) | ITGB3ITGA2BLTA4HCPB2EPOR | |
| SCHEMBL27635585 | 0.85 | SLC1A1 (0.50) | LTA4HALDH1A1KMT2ATDP1 | |
| SCHEMBL8618743 | 0.85 | LTA4H (0.56) | ITGB3ITGA2BLTA4HEPORALDH1A1 | |
| SCHEMBL27635584 | 0.85 | SLC1A1 (0.50) | LTA4HALDH1A1KMT2ATDP1 | |
| Hydrochloric Acid SCHEMBL6671170 | 0.84 | LTA4H (0.55) | ITGB3ITGA2BLTA4HEPOR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1314033-B1 | IMMOBILISED PHOSPHATIDIC ACID PROBE | HOLMES ANDREW BRUCE (GB) | 2009-11-18 | — | — | EP | disclosed |
| US-20040072244-A1 | Immobilised phosphatidic acid probe | HOLMES, ANDREW BRUCE (GB) | 2004-04-15 | — | — | US | disclosed |
| EP-1314033-A2 | IMMOBILISED PHOSPHATIDIC ACID PROBE | THE BABRAHAM INSTITUTE (GB) | 2003-05-28 | — | — | EP | disclosed |
| WO-2002018946-A2 | IMMOBILISED PHOSPHATIDIC ACID PROBE | THE BABRAHAM INSTITUTE (GB) | 2002-03-07 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040072244-A1 | Immobilised phosphatidic acid probe | SGMS2, CHRM2, MBOAT1 | ITGB3 916/4885ITGA2B 1289/4885LTA4H 673/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.