Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 1/20 | 0.48 |
| ▸ | ITGB3 | P05106 | 4/20 | 0.47 |
| ▸ | ITGA2B | P08514 | 4/20 | 0.47 |
| ▸ | EPOR | P19235 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | CPB2 | Q96IY4 | 3/20 | 0.46 |
| ▸ | ECE1 | P42892 | 1/20 | 0.46 |
| ▸ | CPB1 | P15086 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.45 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | AMPD3 | Q01432 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7166074 | 0.98 | ITGB3 (0.49) | LTA4HITGB3ITGA2BEPORALDH1A1 | |
| SCHEMBL4384791 | 0.98 | ITGB3 (0.49) | LTA4HITGB3ITGA2BEPORALDH1A1 | |
| SCHEMBL11588837 | 0.95 | ALDH1A1 (0.47) | LTA4HITGB3ITGA2BEPORALDH1A1 | |
| SCHEMBL8643591 | 0.89 | ALDH1A1 (0.50) | ALDH1A1MAPK1L3MBTL1SLC6A2SLC6A3 | |
| SCHEMBL5242448 | 0.89 | ALDH1A1 (0.50) | ALDH1A1MAPK1L3MBTL1SLC6A2SLC6A3 | |
| SCHEMBL27635584 | 0.86 | SLC1A1 (0.50) | LTA4HALDH1A1KMT2ATDP1 | |
| SCHEMBL27635585 | 0.86 | SLC1A1 (0.50) | LTA4HALDH1A1KMT2ATDP1 | |
| SCHEMBL27486547 | 0.85 | ALDH1A1 (0.44) | LTA4HITGB3ITGA2BEPORALDH1A1 | |
| SCHEMBL25424750 | 0.84 | LTA4H (0.48) | LTA4HITGB3ITGA2BEPORALDH1A1 | |
| SCHEMBL730307 | 0.84 | LTA4H (0.57) | LTA4HEPORALDH1A1MAPK1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 32 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250367332-A1 | PSMA-TARGETED RADIOACTIVE METAL COMPLEX CONTAINING NITROAROMATIC HETEROCYCLIC GROUP AND PREPARATION METHOD | UNIV BEIJING NORMAL (CN) | 2025-12-04 | — | — | US | disclosed |
| EP-4086267-B1 | LIVER-TARGETING COMPOUND HAVING THYROID HORMONE RECEPTOR AGONIST CHARACTERISTICS AND PHARMACEUTICAL COMPOSITION THEREOF | KYLONOVA XIAMEN BIOPHARMA CO LTD (CN) | 2024-07-24 | — | — | EP | disclosed |
| WO-2023231452-A1 | PSMA-TARGETING RADIOACTIVE METAL COMPLEX CONTAINING NITRO AROMATIC HETEROCYCLIC GROUP AND PREPARATION THEREOF | 北京师范大学 | 2023-12-07 | — | — | WO | disclosed |
| CN-116507630-A | PSMA targeted radioactive metal complex containing nitro aromatic heterocyclic group and preparation thereof | 北京师范大学 | 2023-07-28 | — | — | CN | disclosed |
| US-11623938-B2 | Liver-targeting compound having thyroid hormone receptor agonist characteristics and pharmaceutical composition thereof | KYLONOVA (XIAMEN) BIOPHARMA CO., LTD. (CN) | 2023-04-11 | — | — | US | disclosed |
| US-20230065479-A1 | LIVER-TARGETING COMPOUND HAVING THYROID HORMONE RECEPTOR AGONIST CHARACTERISTICS AND PHARMACEUTICAL COMPOSITION THEREOF | KYLONOVA (XIAMEN) BIOPHARMA CO., LTD. (CN) | 2023-03-02 | — | — | US | disclosed |
| EP-4086267-A1 | LIVER-TARGETING COMPOUND HAVING THYROID HORMONE RECEPTOR AGONIST CHARACTERISTICS AND PHARMACEUTICAL COMPOSITION THEREOF | Kylonova (Xiamen) Biopharma Co., Ltd. (CN) | 2022-11-09 | — | — | EP | disclosed |
| WO-2021135335-A1 | LIVER-TARGETING COMPOUND HAVING THYROID HORMONE RECEPTOR AGONIST CHARACTERISTICS AND PHARMACEUTICAL COMPOSITION THEREOF | 厦门甘宝利生物医药有限公司 | 2021-07-08 | — | — | WO | disclosed |
| CN-111116684-B | Liver targeting compound with thyroid hormone receptor agonist characteristic and pharmaceutical composition thereof | 厦门甘宝利生物医药有限公司 | 2020-09-25 | — | — | CN | disclosed |
| CN-111116684-A | Liver targeting compound with thyroid hormone receptor agonist characteristic and pharmaceutical composition thereof | 厦门甘宝利生物医药有限公司 | 2020-05-08 | — | — | CN | disclosed |
| EP-0618891-A1 | METHOD FOR MAKING VALPROIC ACID DERIVATIVES | BECKMAN INSTRUMENTS, INC. (US) | 1994-10-12 | — | — | EP | disclosed |
| WO-1994016330-A1 | METHOD FOR MAKING A PRECONJUGATE | BECKMAN INSTRUMENTS, INC. (US) | 1994-07-21 | — | — | WO | disclosed |
| WO-1994015956-A1 | ENDOTHELIN CONVERTING ENZYME INHIBITORS | THE WELLCOME FOUNDATION LIMITED (GB) | 1994-07-21 | — | — | WO | disclosed |
| WO-1994008608-A1 | AMINO ACID CONJUGATES OF CYCLOHEXAPEPTIDYL AMINES | MERCK & CO., INC. (US) | 1994-04-28 | — | — | WO | disclosed |
| WO-1994006745-A1 | METHOD FOR MAKING VALPROIC ACID DERIVATIVES | BECKMAN INSTRUMENTS, INC. (US) | 1994-03-31 | — | — | WO | disclosed |
| US-4491660-A | ADSORBERS ATTACHED TO A SUPPORT | ABBOTT LABORATORIES (US) | 1985-01-01 | — | — | US | disclosed |
| US-4264514-A | Method and reagents for measuring the level of conjugated bile acids | ABBOTT LABORATORIES (US) | 1981-04-28 | — | — | US | disclosed |
| US-4220598-A | Method and reagents for measuring the level of conjugated bile acids | ABBOTT LABORATORIES (US) | 1980-09-02 | — | — | US | disclosed |
| US-4131727-A | BONDED TO PYRAZOLE | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 1978-12-26 | — | — | US | disclosed |
| US-4111751-A | PYRAZOLE IMMOBILIZED ON A SOLID INSOLUBLE SUPPORT | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 1978-09-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230065479-A1 | LIVER-TARGETING COMPOUND HAVING THYROID HORMONE RECEPTOR AGONIST CHARACTERISTICS AND PHARMACEUTICAL COMPOSITION THEREOF | TSHR, THRA, THRB | LTA4H 601/4885ITGB3 2131/4885ITGA2B 2342/4885 |
| US-11623938-B2 | Liver-targeting compound having thyroid hormone receptor agonist characteristics and pharmaceutical composition thereof | TSHR, THRA, THRB | LTA4H 601/4885ITGB3 2131/4885ITGA2B 2342/4885 |
| US-20250367332-A1 | PSMA-TARGETED RADIOACTIVE METAL COMPLEX CONTAINING NITROAROMATIC HETEROCYCLIC GROUP AND PREPARATION METHOD | PSMA1, PSMA2, PSMA7 | LTA4H 2219/4885ITGB3 3740/4885ITGA2B 1999/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.