SCHEMBL7070839

SCHEMBL7070839

CNc1ccc2c(=O)[nH][nH]c(=O)c2c1

nearest known ligand 0.50

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
▸ KDM4E B2RXH2 2/20 0.50
▸ AR P10275 1/20 0.42
▸ HSD17B10 Q99714 1/20 0.42
▸ BRAF P15056 2/20 0.39
▸ DAO P14920 2/20 0.38
▸ METAP2 P50579 1/20 0.38
▸ PARP15 Q460N3 5/20 0.38
▸ PARP10 Q53GL7 4/20 0.38
▸ SLC18A1 P54219 1/20 0.37
▸ SLC18A2 Q05940 1/20 0.37
▸ AURKA O14965 1/20 0.36
▸ PIK3CD O00329 1/20 0.36
▸ TDP1 Q9NUW8 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3277310 0.79 HSD17B10 (0.46) KDM4EHSD17B10BRAFDAOMETAP2
SCHEMBL438637 0.79 AR (0.47) KDM4EARHSD17B10BRAFPARP15
SCHEMBL8691865 0.76 KDM4E (0.43) KDM4EHSD17B10BRAFDAOMETAP2
SCHEMBL17142230 0.76 KDM4E (0.43) KDM4EARHSD17B10BRAFDAO
SCHEMBL7072330 0.75 BRAF (0.58) KDM4EARHSD17B10BRAFAURKA
SCHEMBL6953743 0.72 PIK3CD (0.40) KDM4EHSD17B10BRAFDAOMETAP2
SCHEMBL3069941 0.72 PIK3CD (0.47) KDM4EARHSD17B10DAOPARP15
SCHEMBL10489398 0.72 HSD17B10 (0.40) KDM4EHSD17B10BRAFDAOMETAP2
SCHEMBL2462837 0.71 KDM4E (0.55) KDM4EHSD17B10DAOMETAP2PARP15
SCHEMBL11347457 0.71 KDM4E (0.50) KDM4EHSD17B10DAOMETAP2PARP15

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1315497-A2 AMINO DERIVATIVES OF 2,3-DIHYDROPHTALAZINE-1,4-DIONE AS IMMUNOCORRECTING AGENTS Medinkor ZMM AG (CH) 2003-06-04 — — EP claimed
WO-2002009681-A2 A METHOD FOR CORRECTING THE IMMUNE SYSTEM OF LIVE BODY MEDINKOR ZMM AG (CH) 2002-02-07 — — WO claimed
US-20030195183-A1 Method for correcting immune system of live body ZHILOV VALERII KHAZHUMURATOVIC (RU) 2003-10-16 — — US disclosed
EP-1315497-A2 AMINO DERIVATIVES OF 2,3-DIHYDROPHTALAZINE-1,4-DIONE AS IMMUNOCORRECTING AGENTS Medinkor ZMM AG (CH) 2003-06-04 — — EP disclosed
WO-2002009681-A2 A METHOD FOR CORRECTING THE IMMUNE SYSTEM OF LIVE BODY MEDINKOR ZMM AG (CH) 2002-02-07 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030195183-A1 Method for correcting immune system of live body IL15, IL5, IL2 KDM4E 823/4885AR 3524/4885HSD17B10 792/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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