Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 2/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.51 |
| ▸ | CLK4 | Q9HAZ1 | 2/20 | 0.51 |
| ▸ | TP53 | P04637 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | USP2 | O75604 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | GLA | P06280 | 1/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.51 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.51 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.51 |
| ▸ | ABL1 | P00519 | 6/20 | 0.50 |
| ▸ | BCR | P11274 | 6/20 | 0.50 |
| ▸ | EGFR | P00533 | 3/20 | 0.46 |
| ▸ | ERBB3 | P21860 | 2/20 | 0.46 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1016320 | 0.81 | ABL1 (0.76) | CYP1A2CYP2C9CLK4TP53MEN1 | |
| SCHEMBL5752589 | 0.78 | TRPV1 (0.63) | CYP1A2CYP2C9CLK4TP53MEN1 | |
| SCHEMBL20816288 | 0.71 | FAAH (0.51) | CYP1A2CYP2C9CLK4TP53MEN1 | |
| SCHEMBL4844440 | 0.71 | FAAH (0.51) | CYP1A2CYP2C9CLK4TP53MEN1 | |
| SCHEMBL30782558 | 0.71 | ABL1 (0.68) | CYP1A2CYP2C9CLK4TP53MEN1 | |
| SCHEMBL2283204 | 0.71 | NPC1 (0.68) | MEN1KMT2AEGFRERBB3SCN9A | |
| SCHEMBL4665672 | 0.70 | CYP1A2 (0.69) | CYP1A2CYP2C9CLK4TP53MEN1 | |
| SCHEMBL27468144 | 0.70 | EGFR (0.61) | CYP1A2CYP2C9CLK4TP53MEN1 | |
| SCHEMBL20137308 | 0.70 | KMO (0.63) | FAAH | |
| SCHEMBL2305280 | 0.70 | TP53 (0.74) | CYP1A2CYP2C9CLK4TP53MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1891004-B1 | PENTAFLUOROSULPHANYL-SUBSTITUTED COMPOUND AND ITS USE FOR PRODUCING MEDICAMENTS | GRUENENTHAL GMBH (DE) | 2009-12-02 | — | — | EP | claimed |
| US-7994167-B2 | Pentafluorosulphanyl-substituted compound and its use for producing medicaments | GRUENENTHAL GMBH (DE) | 2011-08-09 | — | — | US | disclosed |
| US-20090137594-A1 | Pentafluorosulphanyl-Substituted Compound And Its Use For Producing Medicaments | GRUENENTHAL GMGH (DE) | 2009-05-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090137594-A1 | Pentafluorosulphanyl-Substituted Compound And Its Use For Producing Medicaments | FIBP, PFAS, FPR3 | CYP1A2 3740/4885CYP2C9 2662/4885CLK4 3280/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.