Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.51 |
| ▸ | HSPB1 | P04792 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 4/20 | 0.47 |
| ▸ | RECQL | P46063 | 1/20 | 0.47 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.47 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.47 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | APP | P05067 | 1/20 | 0.44 |
| ▸ | HTR1A | P08908 | 1/20 | 0.44 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.44 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.44 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8964023 | 0.81 | ALDH1A1 (0.54) | ALDH1A1TDP1HSPB1MAPTLMNA | |
| SCHEMBL8964199 | 0.80 | ALDH1A1 (0.53) | HTTALDH1A1HSPB1MAPTLMNA | |
| SCHEMBL8964192 | 0.80 | ALDH1A1 (0.50) | HTTALDH1A1HSPB1MAPTLMNA | |
| SCHEMBL5082634 | 0.79 | ALDH1A1 (0.66) | HTTALDH1A1TDP1HSPB1MAPT | |
| SCHEMBL8104896 | 0.79 | HSPB1 (0.56) | HTTALDH1A1HSPB1MAPTLMNA | |
| SCHEMBL22588357 | 0.78 | ALDH1A1 (0.55) | HTTALDH1A1TDP1MAPTLMNA | |
| SCHEMBL11721323 | 0.77 | HSPB1 (0.54) | HTTALDH1A1HSPB1MAPTLMNA | |
| SCHEMBL8875765 | 0.75 | ALDH1A1 (0.48) | ALDH1A1MAPTLMNAHPGDSMN1; SMN2 | |
| SCHEMBL8875762 | 0.75 | ALDH1A1 (0.48) | ALDH1A1MAPTLMNAHPGDSMN1; SMN2 | |
| SCHEMBL30712041 | 0.74 | ALDH1A1 (0.50) | HTTALDH1A1TDP1MAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090233910-A1 | Npy antagonists, preparation and uses | CEREP (FR) | 2009-09-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090233910-A1 | Npy antagonists, preparation and uses | NPY1R, NPY5R, NPY2R | HTT 618/4885ALDH1A1 4542/4885TDP1 2128/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.