SCHEMBL4388333

SCHEMBL4388333

C[C@@H](O)[C@H](NC(=O)[C@@H](N)CCC(=O)O)C(=O)O

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
DPP4 P27487 2/20 0.59
DPP8 Q6V1X1 2/20 0.59
DPP9 Q86TI2 2/20 0.59
CYP1A2 P05177 2/20 0.50
GRM8 O00222 1/20 0.50
GRM6 O15303 1/20 0.50
GRIN2D O15399 1/20 0.50
GRIN3B O60391 1/20 0.50
GSR P00390 1/20 0.50
GRIK1 P39086 1/20 0.50
GRM5 P41594 1/20 0.50
GRIA1 P42261 1/20 0.50
GRIA2 P42262 1/20 0.50
GRIA3 P42263 1/20 0.50
SLC1A3 P43003 1/20 0.50
SLC1A2 P43004 1/20 0.50
SLC1A1 P43005 1/20 0.50
GRIA4 P48058 1/20 0.50
GRIN1 Q05586 1/20 0.50
GRIN2A Q12879 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8529159 1.00 DPP4 (0.59) DPP4DPP8DPP9CYP1A2GRM8
SCHEMBL30924861 0.93 DPP4 (0.52) DPP4DPP8DPP9CYP1A2GRM8
SCHEMBL30361178 0.93 DPP4 (0.52) DPP4DPP8DPP9CYP1A2GRM8
SCHEMBL30562167 0.91 DPP4 (0.51) DPP4DPP8DPP9PDCD1LG2CD274
SCHEMBL31688167 0.90 DPP4 (0.50) DPP4DPP8DPP9CYP1A2GRM8
SCHEMBL29539434 0.90 DPP4 (0.50) DPP4DPP8DPP9CYP1A2GRM8
SCHEMBL29816159 0.89 BACE1 (0.53) DPP4DPP8DPP9CTSDBACE1
SCHEMBL30997362 0.89 BACE1 (0.53) DPP4DPP8DPP9CTSDBACE1
SCHEMBL5970526 0.89 DPP4 (0.58) DPP4DPP8DPP9CYP1A2GRM8
SCHEMBL4388337 0.89 DPP4 (0.58) DPP4DPP8DPP9CYP1A2GRM8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 119 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024132725-A1 SERUM PEPTIDE PATTERNS FOR DIAGNOSTICS OF INTRACRANIAL HEMORRHAGIC STROKE IN HUMANS AND DIFFERENTIAL DIAGNOSIS OF INTRACRANIAL HEMORRHAGIC STROKE FROM ACUTE ISCHEMIC STROKE UNIWERSYTET GDANSKI (PL) 2024-06-27 WO claimed
US-20240158448-A1 MULTIVALENT NANO-'SELF' PEPTIDES AND USES THEREOF NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT 2024-05-16 US claimed
CN-114032271-B Oyster polypeptide and polypeptide powder with uric acid reducing effect, and preparation method and application thereof 浙江工业大学 2024-03-26 CN claimed
WO-2022178263-A1 MULTIVALENT NANO-'SELF' PEPTIDES AND USES THEREOF THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) 2022-08-25 WO claimed
CN-114032271-A Oyster polypeptide and polypeptide powder with uric acid reducing effect as well as preparation method and application of oyster polypeptide and polypeptide powder 浙江工业大学 2022-02-11 CN claimed
CN-109311927-A Sugar-dipeptides conjugates as flavor molecules 雀巢产品技术援助有限公司 2019-02-05 CN claimed
WO-2016112174-A2 Biomarkers of Sleep Deprivation and Cognitive Impairment THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) 2016-07-14 WO claimed
WO-2013188333-A1 BIOMARKERS RELATED TO NEPHROTOXICITY AND METHODS USING THE SAME METABOLON, INC. (US) 2013-12-19 WO claimed
WO-2026107381-A1 DNA POLYMERASE THETA INHIBITORS, COMPOSITIONS THEREOF, COMPOSITIONS FURTHER COMPRISING A DNA DEPENDENT PROTEIN KINASE, AND USES OF BOTH IN GENE EDITING FIELD JUNO THERAPEUTICS, INC. (US) 2026-05-21 WO disclosed
US-20260062697-A1 MODIFIED MESSENGER RNA COMPRISING FUNCTIONAL RNA ELEMENTS MODERNATX INC (US) 2026-03-05 US disclosed
US-12497614-B2 Compositions and methods for editing beta-globin for treatment of hemaglobinopathies VERTEX PHARMACEUTICALS INCORPORATED (US) 2025-12-16 US disclosed
EP-4587116-A2 METHODS AND USES OF MICROBIOME COMPOSITIONS, COMPONENTS, OR METABOLITES FOR TREATING INSULIN-ASSOCIATED DISEASES MarvelBiome, Inc. (US) 2025-07-23 EP disclosed
US-20250215086-A1 ANTI-PD-1 ANTIBODY FORMULATIONS AMGEN INC. (US) 2025-07-03 US disclosed
CN-120005928-A Dynamic regulation and control system, strain, construction method of strain and application of strain in microbial fuel cell 天津科技大学 2025-05-16 CN disclosed
WO-2013070962-A1 METHODS AND USES FOR METABOLIC PROFILING FOR CLOSTRIDIUM DIFFICILE INFECTION THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM (US) 2013-05-16 WO disclosed
US-20130115649-A1 Methods and Reagents for Metabolomics and Histology in a Biological Sample and a Kit for the Same METABOLON, INC. 2013-05-09 US disclosed
US-20120208215-A1 Biomarkers for Pre-Diabetes, Cardiovascular Diseases, and Other Metabolic-Syndrome Related Disorders and Methods Using the Same METABOLON, INC. (US) 2012-08-16 US disclosed
US-8187830-B2 Method for determining insulin sensitivity with biomarkers METABOLON, INC. (US) 2012-05-29 US disclosed
US-20090155826-A1 Biomarkers for pre-diabetes, cardiovascular diseases, and other metabolic-syndrome related disorders and methods using the same METABOLON, INC. (US) 2009-06-18 US disclosed
EP-0885899-A1 Method for obtaining peptide fragments by use of fluorinated organic acids SEIKO INSTRUMENTS INC. (JP) 1998-12-23 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240158448-A1 MULTIVALENT NANO-'SELF' PEPTIDES AND USES THEREOF CD47, CD68, CHERP DPP4 3432/4885DPP8 3949/4885DPP9 3354/4885
US-20260062697-A1 MODIFIED MESSENGER RNA COMPRISING FUNCTIONAL RNA ELEMENTS UPF1, METTL16, RNGTT DPP4 3732/4885DPP8 1876/4885DPP9 2934/4885
US-12497614-B2 Compositions and methods for editing beta-globin for treatment of hemaglobinopathies HBB, HBG1, HBG2 DPP4 3709/4885DPP8 2999/4885DPP9 3324/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.