SCHEMBL4388656

SCHEMBL4388656

O=C(c1[c]cccc1)c1ccccc1O

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LIG1 P18858 1/20 0.48
HPGD P15428 7/20 0.47
KDM4E B2RXH2 5/20 0.47
ALDH1A1 P00352 3/20 0.47
SMN1; SMN2 Q16637 2/20 0.47
CA12 O43570 1/20 0.47
CA1 P00915 1/20 0.47
CA2 P00918 1/20 0.47
HMGB1 P09429 1/20 0.47
CA4 P22748 1/20 0.47
CA6 P23280 1/20 0.47
CA7 P43166 1/20 0.47
CA9 Q16790 1/20 0.47
NAPRT Q6XQN6 1/20 0.47
CA14 Q9ULX7 1/20 0.47
TSHR P16473 3/20 0.45
HSD17B10 Q99714 3/20 0.45
MAPT P10636 2/20 0.45
GSTA1 P08263 2/20 0.44
HIF1A Q16665 2/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL143892 0.81 ALDH1A1 (0.38) ALDH1A1NAPRTTSHRALOX15CYP1A2
SCHEMBL22533769 0.79 HPGD (0.41) HPGDALDH1A1SMN1; SMN2TSHRGAA
SCHEMBL9712664 0.79 CES2 (0.50) HPGDALDH1A1MAPTGAALMNA
SCHEMBL1127556 0.77 CDC25B (0.54) MAPTGAATDP1HTTMEN1
2,2'-Dihydroxybenzphenone SCHEMBL29572496 0.76 HPGD (0.67) LIG1HPGDKDM4EALDH1A1SMN1; SMN2
2,2'-Dihydroxybenzphenone SCHEMBL18422 0.76 HPGD (0.67) LIG1HPGDKDM4EALDH1A1SMN1; SMN2
SCHEMBL7365744 0.75 LMNA (0.49) SMN1; SMN2GAALMNASLC6A2CYP2C19
SCHEMBL10457110 0.75 ALDH1A1 (0.37) KDM4EALDH1A1SMN1; SMN2TSHRMAPT
2,2'-Dihydroxybenzphenone SCHEMBL6652370 0.74 LIG1 (0.64) LIG1HPGDKDM4EALDH1A1SMN1; SMN2
SCHEMBL455832 0.74 LIG1 (0.64) LIG1HPGDKDM4EALDH1A1SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1829854-B1 PROCESS FOR PRODUCING AROMATIC CARBONATE ASAHI KASEI CHEMICALS CORP (JP) 2013-09-04 EP disclosed
US-7629485-B2 Process for producing aromatic carbonate ASAHI KASEI CHEMICALS CORPORATION (JP) 2009-12-08 US disclosed
US-20080177099-A1 Process for Producing Aromatic Carbonate ASAHI KASEI KABUSHIKI KAISHA (JP) 2008-07-24 US disclosed
EP-1829854-A1 PROCESS FOR PRODUCING AROMATIC CARBONATE Asahi Kasei Chemicals Corporation (JP) 2007-09-05 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080177099-A1 Process for Producing Aromatic Carbonate DCLK1, ALK, DCLK3 LIG1 4236/4885HPGD 3545/4885KDM4E 481/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.