Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 3/20 | 0.50 |
| ▸ | CES1 | P23141 | 3/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 4/20 | 0.41 |
| ▸ | HPGD | P15428 | 3/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.40 |
| ▸ | ERCC5 | P28715 | 1/20 | 0.40 |
| ▸ | FEN1 | P39748 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28038726 | 0.81 | CES2 (0.47) | CES2CES1ALDH1A1ALOX15GAA | |
| SCHEMBL143892 | 0.80 | ALDH1A1 (0.38) | CES2CES1ALDH1A1ALOX15MEN1 | |
| SCHEMBL4388656 | 0.79 | LIG1 (0.48) | ALDH1A1ALOX15GAAMEN1KMT2A | |
| SCHEMBL22533769 | 0.78 | HPGD (0.41) | ALDH1A1GAAKMT2AHPGDERCC5 | |
| SCHEMBL28055406 | 0.78 | MAPT (0.53) | ALDH1A1ALOX15GAATDP1MAPT | |
| SCHEMBL10457110 | 0.77 | ALDH1A1 (0.37) | ALDH1A1GAAMEN1KMT2AMAPT | |
| SCHEMBL7365744 | 0.77 | LMNA (0.49) | GAACYP2C9CYP2C19LMNA | |
| SCHEMBL30293901 | 0.77 | CES2 (0.71) | CES2CES1ALDH1A1ALOX15GAA | |
| SCHEMBL250099 | 0.77 | CES2 (0.71) | CES2CES1ALDH1A1ALOX15GAA | |
| SCHEMBL31574193 | 0.75 | CES2 (0.68) | CES2CES1ALDH1A1ALOX15GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5081287-A | Pesticidal polyhalo alkenoic acid esters | FMC CORPORATION (US) | 1992-01-14 | — | — | US | disclosed |