SCHEMBL439197

SCHEMBL439197

C[Si](C)(C)c1[c]cccc1[Si](C)(C)C

nearest known ligand 0.31

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
IDO1 P14902 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12815966 0.76 IDO1 (0.31) IDO1
SCHEMBL12815969 0.76 TSHR (0.35)
SCHEMBL12816615 0.74 ACHE (0.32)
SCHEMBL12816613 0.74 IDO1 (0.31) IDO1
SCHEMBL12817539 0.74 IDO1 (0.31) IDO1
SCHEMBL12817541 0.74 LMNA (0.33)
SCHEMBL5090754 0.71
SCHEMBL12818100 0.71
SCHEMBL17926651 0.71
SCHEMBL12817399 0.71 CA1 (0.42) IDO1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 81 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7855300-B2 Bis(trimethylsilyl)phenyl compound or salt thereof, and use thereof TAIHO PHARMACEUTICAL CO., LTD. (JP) 2010-12-21 US claimed
US-20100210591-A1 BIS(TRIMETHYLSILYL)PHENYL COMPOUND OR SALT THEREOF, AND USE THEREOF TAIHO PHARMACEUTICAL CO., LTD. (JP) 2010-08-19 US claimed
EP-2202235-A1 BIS(TRIMETHYLSILYL)PHENYL COMPOUND OR SALT THEREOF, AND USE THEREOF Taiho Pharmaceutical Co., Ltd. (JP) 2010-06-30 EP claimed
US-4263401-A Thermoplastic, elastomeric polystyrene/diorganopolysiloxane block copolymers RHONE-POULENC INDUSTRIES (FR) 1981-04-21 US claimed
US-20240218088-A1 METAL COMPLEX CATALYST FOR THE POLYMERIZATION OF OLEFINS ARLANXEO NETHERLANDS B.V. (NL) 2024-07-04 US disclosed
EP-4330297-A1 METAL COMPLEX CATALYST FOR THE POLYMERIZATION OF OLEFINS Arlanxeo Netherlands B.V. (NL) 2024-03-06 EP disclosed
EP-4320135-A1 METAL COMPLEXES WITH SULFILIMINE-TYPE LIGANDS AND THEIR USE AS POLYMERIZATION CATALYSTS Arlanxeo Netherlands B.V. (NL) 2024-02-14 EP disclosed
CN-117062846-A Metal complex catalyst for olefin polymerization 阿朗新科荷兰有限公司 2023-11-14 CN disclosed
CN-117043170-A Metal complexes with thioimine ligands and their use as polymerization catalysts 阿朗新科荷兰有限公司 2023-11-10 CN disclosed
WO-2022229310-A1 METAL COMPLEX CATALYST FOR THE POLYMERIZATION OF OLEFINS ARLANXEO NETHERLANDS B.V. (NL) 2022-11-03 WO disclosed
EP-1964860-B1 ETHYLENE POLYMER, CATALYST FOR PRODUCTION OF ETHYLENE POLYMER, AND PROCESS FOR PRODUCTION OF ETHYLENE POLYMER TOSOH CORP (JP) 2017-07-05 EP disclosed
EP-1473323-B1 Polyethylene composition and process for producing same TOSOH CORP (JP) 2016-04-27 EP disclosed
US-7233019-B2 Electroluminescent silylated pyrenes, and devices made with such compounds E. I. DU PONT DE NEMOURS AND COMPANY (US) 2007-06-19 US disclosed
US-20050238910-A1 Electroluminescent silylated pyrenes, and devices made with such compounds LG CHEM, LTD. (KR) 2005-10-27 US disclosed
EP-1473323-A1 Polyethylene composition and process for producing same Tosoh Corporation (JP) 2004-11-03 EP disclosed
US-20040214953-A1 Polyethylene composition and process for producing same TOSOH CORPORATION 2004-10-28 US disclosed
EP-1397188-A1 DEFOAMING AGENT AND/OR DEAERATING AGENT BASED ON OIL-IN-WATER DISPERSIONS BASF AKTIENGESELLSCHAFT (DE) 2004-03-17 EP disclosed
WO-2002098532-A1 DEFOAMING AGENT AND/OR DEAERATING AGENT BASED ON OIL-IN-WATER DISPERSIONS BASF AKTIENGESELLSCHAFT (DE) 2002-12-12 WO disclosed
US-4263401-A Thermoplastic, elastomeric polystyrene/diorganopolysiloxane block copolymers RHONE-POULENC INDUSTRIES (FR) 1981-04-21 US disclosed
US-4229318-A Manufacture of a titanium-containing component for catalysts of the Ziegler-Natta type BASF AKTIENGESELLSCHAFT (DE) 1980-10-21 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050238910-A1 Electroluminescent silylated pyrenes, and devices made with such compounds EPCAM, LMNB2, CTCF IDO1 3858/4885
US-20100210591-A1 BIS(TRIMETHYLSILYL)PHENYL COMPOUND OR SALT THEREOF, AND USE THEREOF RARA, RARB, RXRA IDO1 4216/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.