Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.49 |
| ▸ | NPC1 | O15118 | 2/20 | 0.49 |
| ▸ | RECQL | P46063 | 1/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.46 |
| ▸ | CYP2A13 | Q16696 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
| ▸ | PCSK9 | Q8NBP7 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | PDE2A | O00408 | 1/20 | 0.38 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21022692 | 0.82 | CYP2A6 (0.69) | NPC1ALDH1A1CYP2A6CYP2A13HSD17B10 | |
| SCHEMBL197196 | 0.77 | PCSK9 (0.60) | KDM4ENPC1RECQLNPSR1ALDH1A1 | |
| SCHEMBL5163455 | 0.77 | KDM4E (0.50) | KDM4ENPC1RECQLNPSR1ALDH1A1 | |
| SCHEMBL16263093 | 0.77 | NPC1 (0.53) | KDM4ENPC1RECQLNPSR1ALDH1A1 | |
| SCHEMBL15002051 | 0.76 | ALDH1A1 (0.44) | KDM4ENPC1RECQLNPSR1ALDH1A1 | |
| SCHEMBL5329723 | 0.72 | PKM (0.49) | KDM4ENPC1ALDH1A1HSD17B10MAPT | |
| SCHEMBL13484020 | 0.72 | ENPP3 (0.44) | KDM4ENPC1RECQLNPSR1ALDH1A1 | |
| SCHEMBL29094518 | 0.71 | ALOX15 (0.41) | KDM4ENPC1RECQLNPSR1ALDH1A1 | |
| SCHEMBL646282 | 0.71 | ALOX15 (0.47) | KDM4ENPC1RECQLNPSR1ALDH1A1 | |
| SCHEMBL25409767 | 0.70 | ALOX15 (0.43) | KDM4ENPC1RECQLNPSR1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1756192-B1 | PARTICULATE MATERIALS | EXILICA LTD (GB) | 2014-07-02 | — | — | EP | disclosed |
| EP-2562148-A2 | Particulate polymer materials | Exilica Limited (GB) | 2013-02-27 | — | — | EP | disclosed |
| US-20120064348-A1 | Particulate materials | LYNCH DANIEL ERIC (GB) | 2012-03-15 | — | — | US | disclosed |
| US-8084533-B2 | addition-condensation copolymer of 1-methylpyrrol and squaraine, use as a support with hollow silica shells for an active agent Diclofenac Sodium salt; reservoirs or encapsulating agents; pyrolysis of a glass-coated polymer | EXILICA LIMITED (GB) | 2011-12-27 | — | — | US | disclosed |
| US-20080188611-A1 | Particulate Materials | COVENTRY UNIVERSITY (GB) | 2008-08-07 | — | — | US | disclosed |