Water

Water

SCHEMBL4393002

O.[Br-].[Br-].[Br-].[Br-].[Ru+4]

nearest known ligand 0.00

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

ABCC9ABL1ACEACHEACVR1ADORA1ADORA2AADORA2BADORA3ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3AGTR1ALOX5ATP4AATP4BBCRBTKCACNA1ACACNA1BCACNA1CCACNA1DCACNA1ECACNA1FCACNA1GCACNA1HCACNA1ICACNA1SCACNA2D1CACNA2D2CACNA2D3CACNA2D4CACNB1CACNB2CACNB3CACNB4CACNG1CACNG2CACNG3CACNG4CACNG5CACNG6CACNG7CACNG8CALCRLCFBCHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNB1CHRNDCHRNECHRNGCRBNCUL4ACXCR1CXCR2DDB1DDCDHFRDPP4DRD2DRD3DRD4EGFRERBB2ERBB4ESR1ESR2FDPSFKBP1AFLT1FLT3FLT4GARTGHSRGRIA1GRIA2GRIA3GRIA4GRIK1GRIK2GRIK3GRIK4GRIK5GRIN2AGSK3AGSK3BHDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HTR1AHTR1BHTR1DHTR1EHTR1FHTR2AHTR2BHTR2CHTR3AHTR3BHTR3CHTR3DHTR3EHTR4HTR5AHTR6HTR7IDH1IDH2IMPA1ITGA2BITGB3JAK1JAK2JAK3KCNJ11KCNK3KCNK9KDRKITMEN1METMMP1MMP13MMP7MMP8NANOD2NS5bODC1OPG057OPRD1OPRK1OPRM1PPARP1PARP2PDE3APDE3BPDE4APDE4BPDE4CPDE4DPDGFRBPIK3CAPIK3CBPIK3CDPIK3CGPIK3R1PIK3R2PIK3R3PIK3R5PKLRPPARDPPATPTGS1PTGS2RBX1ROCK1ROCK2RRM1RRM2RRM2BSCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASCNN1ASCNN1BSCNN1GSIGMAR1SLC10A2SLC5A2SLC6A2SLC6A3SLC6A4SLC9A3SYKTACR1THRATHRBTOP1TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYK2TYMSVDRampCblablaT-3blaT-4blaT-5blaT-6blaUOE-1dacAdacBdacCfolAfolPftsIgyrAgyrBileSmecAmrcAmrcBmrdAparCparEpbp2pbp4pbpApbpFrplArplBrplCrplDrplErplFrplIrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmE2rpmFrpmGrpmG1rpmG2rpmG3rpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUthyAykgMykgO

The experimentally established mechanism targets of Water. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Water SCHEMBL465936 0.82
Water SCHEMBL10999235 0.82
Water SCHEMBL10938611 0.82
Water SCHEMBL15756782 0.82
Water SCHEMBL9043508 0.82
Water SCHEMBL25376347 0.82
Water SCHEMBL16822414 0.82
Water SCHEMBL1323986 0.82
Water SCHEMBL22776065 0.82
Water SCHEMBL117776 0.82

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 39 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-102600888-B Benzene hydrogenation catalyst as well as preparation method and application thereof UNIV XIANGTAN 2015-02-18 CN claimed
CN-102600888-A Benzene hydrogenation catalyst as well as preparation method and application thereof UNIV XIANGTAN 2012-07-25 CN claimed
US-7629288-B2 From fluid containing hydrogen and carbon monoxide; impregnation, calcining CONOCOPHILLIPS COMPANY (US) 2009-12-08 US claimed
US-20060128554-A1 Catalyst composition comprising ruthenium and a treated silica support component and processes therefor and therewith for preparing high molecular weight hydrocarbons such as polymethylene CONOCOPHILLIPS COMPANY (US) 2006-06-15 US claimed
US-6956064-B2 Catalyst composition comprising ruthenium and zirconium and processes therefor and therewith for preparing high molecular weight hydrocarbons such as polymethylene CONOCOPHILLIPS COMPANY (US) 2005-10-18 US claimed
US-20040127583-A1 Catalyst composition comprising ruthenium and zirconium and processes therefor and therewith for preparing high molecular weight hydrocarbons such as polymethylene PHILLIPS PETROLEUM COMPANY 2004-07-01 US claimed
US-20040127584-A1 Chemical vapor deposition synthesis of polymerization catalyst composition PHILLIPS PETROLEUM COMPANY 2004-07-01 US claimed
US-20040087672-A1 Catalyst composition comprising ruthenium and a treated silica support component and processes therefor and therewith for preparing high molecular weight hydrocarbons such as polymethylene PHILLIPS PETROLEUM COMPANY 2004-05-06 US claimed
US-5719301-A Method of conjugating double bonds in drying oils ARCHER DANIELS MIDLAND COMPANY (US) 1998-02-17 US claimed
CN-115318282-B Ruthenium-titanium bi-component catalyst and preparation method and application thereof 中国石油天然气股份有限公司 2024-07-19 CN disclosed
WO-2023039068-A1 COMPOSITIONS AND METHODS FOR SYNTHESIS OF PEPTIDE NUCLEIC ACID INTERMEDIATES NEUBASE THERAPEUTICS, INC. (US) 2023-03-16 WO disclosed
CN-115318282-A Ruthenium-titanium bi-component catalyst and preparation method and application thereof 中国石油天然气股份有限公司 2022-11-11 CN disclosed
CN-115141093-A Preparation method of ruthenium acetate 浙江微通催化新材料有限公司 2022-10-04 CN disclosed
CN-111167505-B High-stability ruthenium-based catalyst and preparation method and application thereof 万华化学集团股份有限公司 2022-09-20 CN disclosed
US-20040087672-A1 Catalyst composition comprising ruthenium and a treated silica support component and processes therefor and therewith for preparing high molecular weight hydrocarbons such as polymethylene PHILLIPS PETROLEUM COMPANY 2004-05-06 US disclosed
WO-2004016350-A1 PROCESS FOR CONJUGATING CARBON-CARBON DOUBLE BONDS IN OILS ARCHER-DANIELS-MIDLAND COMPANY (US) 2004-02-26 WO disclosed
US-6696581-B1 HEATING IN ORGANIC SOLVENT CONTAINING RUTHENIUM TRICHLORIDE HYDRATE ARCHER-DANIELS-MIDLAND COMPANY 2004-02-24 US disclosed
US-5942058-A BLEND OF POLYMER AND TRIGLYCERIDES ARCHER DANIELS MIDLAND COMPANY (US) 1999-08-24 US disclosed
US-5719301-A Method of conjugating double bonds in drying oils ARCHER DANIELS MIDLAND COMPANY (US) 1998-02-17 US disclosed
EP-0780441-A2 Co-adhesive system, for bonding wood, fibers, or agriculture based composite materials ARCHER-DANIELS-MIDLAND COMPANY (US) 1997-06-25 EP disclosed