Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR4A2 | P43354 | 3/20 | 0.54 |
| ▸ | NCF1 | P14598 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | HSP90AA1 | P07900 | 3/20 | 0.39 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | CASP6 | P55212 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | BCHE | P06276 | 1/20 | 0.35 |
| ▸ | ACHE | P22303 | 1/20 | 0.35 |
| ▸ | APAF1 | O14727 | 1/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | UBE2N | P61088 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | CASP1 | P29466 | 1/20 | 0.35 |
| ▸ | CASP7 | P55210 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14712693 | 0.81 | POLB (0.52) | NR4A2POLBMAPTLMNAKMT2A | |
| SCHEMBL28842256 | 0.78 | POLB (0.41) | NR4A2POLBMAPTHSP90AA1LMNA | |
| SCHEMBL441901 | 0.75 | MCHR1 (0.43) | POLBMAPTLMNABCHEACHE | |
| SCHEMBL9391555 | 0.73 | NQO2 (0.40) | KMT2A | |
| SCHEMBL1615754 | 0.72 | ALDH1A1 (0.46) | POLBMAPTKMT2AMAPK1ALDH1A1 | |
| SCHEMBL29617388 | 0.72 | ALDH1A1 (0.46) | POLBMAPTKMT2AMAPK1ALDH1A1 | |
| SCHEMBL8436758 | 0.72 | KMT2A (0.42) | POLBMAPTLMNAKMT2AAPAF1 | |
| SCHEMBL8946324 | 0.72 | NQO2 (0.61) | MAPTKMT2AKDM4EALDH1A1 | |
| SCHEMBL437497 | 0.70 | NR4A2 (0.62) | NR4A2NCF1MAPTHSP90AA1HSP90AB1 | |
| SCHEMBL438119 | 0.70 | NR4A2 (1.00) | NR4A2NCF1POLBMAPTHSP90AA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120065166-A1 | Bone Modulators And Methods Therewith | ESPINA VIRGINIA (US) | 2012-03-15 | — | — | US | disclosed |