Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | NQO2 | P16083 | 4/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | GABRA2 | P47869 | 4/20 | 0.44 |
| ▸ | GABRB2 | P47870 | 4/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | AURKA | O14965 | 1/20 | 0.41 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.41 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29617388 | 1.00 | ALDH1A1 (0.46) | ALDH1A1POLBMAPK1NQO2CYP1A2 | |
| SCHEMBL9462723 | 0.85 | NQO2 (0.52) | ALDH1A1NQO2CYP1A2GABRA2GABRB2 | |
| SCHEMBL8946324 | 0.85 | NQO2 (0.61) | ALDH1A1NQO2NPC1MAPTRAB9A | |
| SCHEMBL8946246 | 0.82 | CYP1A2 (0.42) | ALDH1A1MAPK1NQO2CYP1A2GABRA2 | |
| SCHEMBL19152266 | 0.82 | GABRA2 (0.42) | ALDH1A1POLBMAPK1NQO2CYP1A2 | |
| SCHEMBL9391555 | 0.79 | NQO2 (0.40) | NQO2CYP1A2MEN1KMT2A | |
| SCHEMBL9463492 | 0.78 | NQO2 (0.47) | ALDH1A1NQO2CYP1A2GABRA2GABRB2 | |
| SCHEMBL3327719 | 0.76 | CYP1A2 (0.61) | ALDH1A1POLBMAPK1CYP1A2GABRA2 | |
| SCHEMBL1617936 | 0.76 | GABRA2 (0.42) | ALDH1A1MAPK1NQO2CYP1A2GABRA2 | |
| SCHEMBL17372703 | 0.74 | GLP1R (0.48) | ALDH1A1MAPK1CYP1A2GABRA2GABRB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4227297-A1 | PROCESS FOR PREPARING DIPHENYLUREIDO-DIHALOKYNURENIC ACIDS AND TOSYLATE ADDITION SALTS THEREOF | Lohocla Research Corporation (US) | 2023-08-16 | — | — | EP | disclosed |
| EP-4227297-A1 | PROCESS FOR PREPARING DIPHENYLUREIDO-DIHALOKYNURENIC ACIDS AND TOSYLATE ADDITION SALTS THEREOF | Lohocla Research Corporation (US) | 2023-08-16 | — | — | EP | disclosed |
| US-20220162168-A1 | PROCESS FOR PREPARING DIPHENYLUREIDO-DIHALOKYNURENIC ACIDS AND TOSYLATE ADDITION SALTS THEREOF | LOHOCLA RESEARCH CORPORATION | 2022-05-26 | — | — | US | disclosed |
| US-20220162168-A1 | PROCESS FOR PREPARING DIPHENYLUREIDO-DIHALOKYNURENIC ACIDS AND TOSYLATE ADDITION SALTS THEREOF | LOHOCLA RESEARCH CORPORATION | 2022-05-26 | — | — | US | disclosed |
| US-11130737-B2 | Multifunctional aminoquinoline therapeutic agents | LOHOCLA RESEARCH CORPORATION (US) | 2021-09-28 | — | — | US | disclosed |
| EP-3846813-A1 | ANALGESIC COMPOSITIONS | Lohocla Research Corporation (US) | 2021-07-14 | — | — | EP | disclosed |
| US-10875831-B1 | Process for preparing 1,4-dihydro-4-oxoquinoline-2-carboxylates and 4-aminoquinoline compounds therefrom | LOHOCLA RESEARCH CORPORATION (US) | 2020-12-29 | — | — | US | disclosed |
| US-10875831-B1 | Process for preparing 1,4-dihydro-4-oxoquinoline-2-carboxylates and 4-aminoquinoline compounds therefrom | LOHOCLA RESEARCH CORPORATION (US) | 2020-12-29 | — | — | US | disclosed |
| US-20200095204-A1 | MULTIFUNCTIONAL AMINOQUINOLINE THERAPEUTIC AGENTS | LOHOCLA RESEARCH CORPORATION | 2020-03-26 | — | — | US | disclosed |
| US-10435371-B2 | Multifunctional aminoquinoline therapeutic agent | LOHOCLA RESEARCH CORPORATION (US) | 2019-10-08 | — | — | US | disclosed |
| US-20110184018-A1 | METHOD FOR TREATING PERIPHERAL NEUROPATHIC PAIN | LOHOCLA RESEARCH CORPORATION (US) | 2011-07-28 | — | — | US | disclosed |
| US-7923458-B2 | Method for treating chronic pain | LOHOCLA RESEARCH CORPORATION (US) | 2011-04-12 | — | — | US | disclosed |
| US-7923458-B2 | Method for treating chronic pain | LOHOCLA RESEARCH CORPORATION (US) | 2011-04-12 | — | — | US | disclosed |
| US-7923458-B2 | Method for treating chronic pain | LOHOCLA RESEARCH CORPORATION (US) | 2011-04-12 | — | — | US | disclosed |
| US-20090137627-A1 | Method for Treating Chronic Pain | LOHOCLA RESEARCH CORPORATION | 2009-05-28 | — | — | US | disclosed |
| US-20090137627-A1 | Method for Treating Chronic Pain | LOHOCLA RESEARCH CORPORATION | 2009-05-28 | — | — | US | disclosed |
| US-20090137627-A1 | Method for Treating Chronic Pain | LOHOCLA RESEARCH CORPORATION | 2009-05-28 | — | — | US | disclosed |
| EP-1951238-A2 | METHOD FOR TREATING CHRONIC PAIN | Lohocla Research Corporation (US) | 2008-08-06 | — | — | EP | disclosed |
| WO-2007044682-A2 | METHOD FOR TREATING CHRONIC PAIN | LOHOCLA RESEARCH CORPORATION (US) | 2007-04-19 | — | — | WO | disclosed |
| WO-2007044682-A2 | METHOD FOR TREATING CHRONIC PAIN | LOHOCLA RESEARCH CORPORATION (US) | 2007-04-19 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11130737-B2 | Multifunctional aminoquinoline therapeutic agents | OPRK1, OPRM1, OPRD1 | ALDH1A1 233/4885POLB 2632/4885MAPK1 2310/4885 |
| US-20090137627-A1 | Method for Treating Chronic Pain | OPRK1, AADAT, BDKRB2 | ALDH1A1 930/4885POLB 4165/4885MAPK1 3630/4885 |
| US-20110184018-A1 | METHOD FOR TREATING PERIPHERAL NEUROPATHIC PAIN | CNR1, CNR2, OPRK1 | ALDH1A1 2774/4885POLB 3577/4885MAPK1 1719/4885 |
| US-20200095204-A1 | MULTIFUNCTIONAL AMINOQUINOLINE THERAPEUTIC AGENTS | OPRK1, OPRM1, OPRD1 | ALDH1A1 233/4885POLB 2632/4885MAPK1 2310/4885 |
| US-10875831-B1 | Process for preparing 1,4-dihydro-4-oxoquinoline-2-carboxylates and 4-aminoquinoline compounds therefrom | KMO, THEM6, HADHA | ALDH1A1 1660/4885POLB 3846/4885MAPK1 2774/4885 |
| US-10435371-B2 | Multifunctional aminoquinoline therapeutic agent | OPRK1, OPRM1, OPRD1 | ALDH1A1 220/4885POLB 2753/4885MAPK1 2551/4885 |
| US-20220162168-A1 | PROCESS FOR PREPARING DIPHENYLUREIDO-DIHALOKYNURENIC ACIDS AND TOSYLATE ADDITION SALTS THEREOF | KMO, KYNU, PAH | ALDH1A1 979/4885POLB 3643/4885MAPK1 1167/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.