Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | TP53 | P04637 | 3/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | FAAH | O00519 | 5/20 | 0.34 |
| ▸ | GYS1 | P13807 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | GLA | P06280 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4405668 | 0.93 | MCHR1 (0.36) | ALDH1A1TSHRHTTFAAHMEN1 | |
| SCHEMBL914587 | 0.88 | ALDH1A1 (0.40) | NPSR1ALDH1A1TP53RAB9AMEN1 | |
| SCHEMBL4410349 | 0.86 | HRH3 (0.42) | NPSR1ALDH1A1TP53TSHRHTT | |
| SCHEMBL4396457 | 0.86 | HRH3 (0.42) | NPSR1ALDH1A1TP53TSHRHTT | |
| SCHEMBL4411339 | 0.83 | HTR7 (0.38) | NPSR1ALDH1A1TP53GYS1RAB9A | |
| SCHEMBL4404600 | 0.82 | ALDH1A1 (0.36) | ALDH1A1TSHRHTTSMN1; SMN2KDM4E | |
| Hydrochloric Acid SCHEMBL4405691 | 0.81 | LMNA (0.37) | ALDH1A1TSHRHTTKDM4ELMNA | |
| SCHEMBL4400753 | 0.81 | ALDH1A1 (0.38) | ALDH1A1TSHRHTTSMN1; SMN2KDM4E | |
| SCHEMBL914266 | 0.81 | DRD4 (0.40) | ALDH1A1TSHRMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL4403425 | 0.79 | DYRK1A (0.37) | NPSR1ALDH1A1GYS1RAB9AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1720859-B1 | CHEMOKINE RECEPTOR ANTAGONISTS | NOVARTIS AG (CH) | 2009-12-23 | — | — | EP | claimed |