Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | TP53 | P04637 | 4/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | FAAH | O00519 | 3/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | HTR7 | P34969 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4410349 | 1.00 | HRH3 (0.42) | HRH3ALDH1A1TP53KDM4ENPSR1 | |
| SCHEMBL4411339 | 0.93 | HTR7 (0.38) | ALDH1A1TP53KDM4ENPSR1KMT2A | |
| SCHEMBL4396992 | 0.92 | KMT2A (0.41) | KDM4EFAAHKMT2AKCNH2 | |
| SCHEMBL4396410 | 0.90 | L3MBTL1 (0.40) | HRH3ALDH1A1KDM4EHPGDL3MBTL1 | |
| SCHEMBL4396337 | 0.89 | HTR7 (0.43) | ALDH1A1TP53KDM4ELMNAFAAH | |
| SCHEMBL4405673 | 0.88 | CHRM3 (0.42) | HRH3KCNH2DRD2 | |
| SCHEMBL4394199 | 0.88 | CHRM3 (0.41) | FAAHHTR7HTR1A | |
| SCHEMBL913726 | 0.87 | ALDH1A1 (0.45) | HRH3ALDH1A1TP53KDM4ENPSR1 | |
| SCHEMBL916260 | 0.87 | ALDH1A1 (0.45) | HRH3ALDH1A1TP53KDM4ENPSR1 | |
| SCHEMBL4401571 | 0.86 | HPGDS (0.39) | HTR7HTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1720859-B1 | CHEMOKINE RECEPTOR ANTAGONISTS | NOVARTIS AG (CH) | 2009-12-23 | — | — | EP | claimed |