Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR7 | P34969 | 5/20 | 0.38 |
| ▸ | PRKAB2 | O43741 | 1/20 | 0.37 |
| ▸ | PRKAG1 | P54619 | 1/20 | 0.37 |
| ▸ | PRKAA2 | P54646 | 1/20 | 0.37 |
| ▸ | PRKAA1 | Q13131 | 1/20 | 0.37 |
| ▸ | PRKAG3 | Q9UGI9 | 1/20 | 0.37 |
| ▸ | PRKAG2 | Q9UGJ0 | 1/20 | 0.37 |
| ▸ | PRKAB1 | Q9Y478 | 1/20 | 0.37 |
| ▸ | HTR1A | P08908 | 2/20 | 0.37 |
| ▸ | DRD2 | P14416 | 1/20 | 0.37 |
| ▸ | HTR6 | P50406 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.36 |
| ▸ | LTA4H | P09960 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4410349 | 0.93 | HRH3 (0.42) | HTR7HTR1ADRD2HTR6KDM4E | |
| SCHEMBL4396457 | 0.93 | HRH3 (0.42) | HTR7HTR1ADRD2HTR6KDM4E | |
| SCHEMBL4551165 | 0.92 | SIGMAR1 (0.40) | DRD2KMT2ADYRK1A | |
| SCHEMBL4403425 | 0.90 | DYRK1A (0.37) | KDM4EMEN1RAB9AKMT2ANPSR1 | |
| SCHEMBL914477 | 0.87 | HTR7 (0.42) | HTR7HTR1ADRD2HTR6KDM4E | |
| SCHEMBL4403763 | 0.85 | TLR9 (0.42) | HTR7DYRK1AWNT1 | |
| SCHEMBL4396992 | 0.85 | KMT2A (0.41) | KDM4EMEN1KMT2ADYRK1A | |
| SCHEMBL4398653 | 0.83 | MCHR1 (0.37) | KMT2ADYRK1A | |
| SCHEMBL4396412 | 0.83 | NPSR1 (0.36) | KDM4EMEN1RAB9AKMT2ANPSR1 | |
| SCHEMBL4396410 | 0.83 | L3MBTL1 (0.40) | KDM4ERXFP1DYRK1AALDH1A1WNT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1720859-B1 | CHEMOKINE RECEPTOR ANTAGONISTS | NOVARTIS AG (CH) | 2009-12-23 | — | — | EP | claimed |