Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APAF1 | O14727 | 6/20 | 0.90 |
| ▸ | CASP3 | P42574 | 6/20 | 0.90 |
| ▸ | CASP9 | P55211 | 6/20 | 0.90 |
| ▸ | CYCS | P99999 | 6/20 | 0.90 |
| ▸ | ACHE | P22303 | 1/20 | 0.44 |
| ▸ | CCR5 | P51681 | 1/20 | 0.41 |
| ▸ | P2RX7 | Q99572 | 8/20 | 0.38 |
| ▸ | CCKBR | P32239 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4388693 | 0.94 | APAF1 (1.00) | APAF1CASP3CASP9CYCSACHE | |
| SCHEMBL4401180 | 0.90 | APAF1 (0.91) | APAF1CASP3CASP9CYCSACHE | |
| SCHEMBL4395653 | 0.90 | APAF1 (0.90) | APAF1CASP3CASP9CYCSACHE | |
| SCHEMBL4398368 | 0.88 | APAF1 (0.87) | APAF1CASP3CASP9CYCSACHE | |
| SCHEMBL4541497 | 0.88 | APAF1 (0.86) | APAF1CASP3CASP9CYCSACHE | |
| SCHEMBL4391634 | 0.88 | APAF1 (0.86) | APAF1CASP3CASP9CYCSACHE | |
| SCHEMBL4394060 | 0.86 | APAF1 (0.75) | APAF1CASP3CASP9CYCSACHE | |
| SCHEMBL4396565 | 0.86 | APAF1 (0.83) | APAF1CASP3CASP9CYCSACHE | |
| SCHEMBL4395693 | 0.84 | APAF1 (0.79) | APAF1CASP3CASP9CYCSACHE | |
| SCHEMBL3698065 | 0.83 | APAF1 (0.90) | APAF1CASP3CASP9CYCSACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1963357-B1 | COMPOUNDS FOR THE INHIBITION OF APOPTOSIS | SALVAT LAB SA (ES) | 2009-12-09 | — | — | EP | disclosed |
| US-20090298781-A1 | COMPOUNDS FOR THE INHIBITION OF APOPTOSIS | CONSEJO SUPERIOR DE (ES) | 2009-12-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090298781-A1 | COMPOUNDS FOR THE INHIBITION OF APOPTOSIS | BAX, BCL2, CASP3 | APAF1 27/4885CASP3 3/4885CASP9 9/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.