SCHEMBL4397589

SCHEMBL4397589

CCCCCC(=O)CCC(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)F

nearest known ligand 0.44

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
FAAH O00519 11/20 0.44
KMT2A Q03164 2/20 0.44
MAPT P10636 1/20 0.44
CES1 P23141 9/20 0.43
CES2 O00748 6/20 0.43
MEN1 O00255 1/20 0.43
CYP1A2 P05177 1/20 0.43
HSD17B10 Q99714 1/20 0.43
HAO1 Q9UJM8 1/20 0.37
AKR1B1 P15121 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7255335 0.85 THRB (0.35)
SCHEMBL7258080 0.85 THRB (0.41)
SCHEMBL22118497 0.79 FAAH (0.43) FAAHKMT2AMAPTCES1CES2
SCHEMBL8752134 0.78 DGKA (0.54) FAAHKMT2AMAPTCES1CES2
SCHEMBL13826951 0.77 CES2 (0.38) FAAHKMT2ACES1CES2MEN1
SCHEMBL17691447 0.77 CES2 (0.38) FAAHKMT2ACES1CES2MEN1
SCHEMBL6291255 0.77 CES2 (0.38) FAAHKMT2ACES1CES2MEN1
SCHEMBL11882704 0.77 CES2 (0.38) FAAHKMT2ACES1CES2MEN1
SCHEMBL6139936 0.77 THRB (0.34)
SCHEMBL8752108 0.76 DGKA (0.57) FAAHKMT2AMAPTCES1CES2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2128117-A2 MODIFIER FOR EXPLOSIVES Obshestvo S Ogranichennoy Otvetstvennjctyu "Ifokhim" (RU) 2009-12-02 EP disclosed
EP-2024287-A1 METHODS AND COMPOSITIONS FOR CONTROLLED AND SUSTAINED PRODUCTION AND DELIVERY OF PEROXIDES Virginia Commonwealth University (US) 2009-02-18 EP disclosed
WO-2007134304-A1 METHODS AND COMPOSITIONS FOR CONTROLLED AND SUSTAINED PRODUCTION AND DELIVERY OF PEROXIDES VIRGINIA COMMONWEALTH UNIVERSITY (US) 2007-11-22 WO disclosed