Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HAVCR2 | Q8TDQ0 | 1/20 | 0.53 |
| ▸ | CLCN2 | P51788 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.39 |
| ▸ | DPP4 | P27487 | 1/20 | 0.38 |
| ▸ | EGFR | P00533 | 2/20 | 0.37 |
| ▸ | KMO | O15229 | 3/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | FYN | P06241 | 1/20 | 0.36 |
| ▸ | SRC | P12931 | 1/20 | 0.36 |
| ▸ | TEC | P42680 | 1/20 | 0.36 |
| ▸ | BTK | Q06187 | 1/20 | 0.36 |
| ▸ | ITK | Q08881 | 1/20 | 0.36 |
| ▸ | CSF1R | P07333 | 1/20 | 0.36 |
| ▸ | IKBKB | O14920 | 1/20 | 0.36 |
| ▸ | PDE5A | O76074 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL435825 | 0.89 | HAVCR2 (0.50) | HAVCR2CLCN2ALDH1A1MRGPRX4EGFR | |
| SCHEMBL440068 | 0.84 | HAVCR2 (0.63) | HAVCR2ALDH1A1KMOKMT2AMAPT | |
| SCHEMBL438246 | 0.84 | DPP4 (0.56) | DPP4KMT2AMAPTPDE5AMEN1 | |
| SCHEMBL440283 | 0.81 | DYRK1A (0.39) | ALDH1A1KMT2AMAPTKDM4EIKBKB | |
| SCHEMBL436999 | 0.77 | NQO2 (0.36) | ALDH1A1KMT2AMAPTKDM4EMEN1 | |
| SCHEMBL442158 | 0.76 | HAVCR2 (0.54) | HAVCR2CLCN2ALDH1A1KMT2AMAPT | |
| SCHEMBL440489 | 0.74 | DPP4 (0.53) | DPP4KMT2AMAPTMEN1NPC1 | |
| SCHEMBL439862 | 0.72 | HAVCR2 (0.63) | HAVCR2KMT2AMEN1 | |
| SCHEMBL437260 | 0.71 | HAVCR2 (0.67) | HAVCR2ALDH1A1KMT2AMAPTKDM4E | |
| SCHEMBL437796 | 0.70 | NPC1 (0.54) | ALDH1A1KMT2AMAPTKDM4EMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120065166-A1 | Bone Modulators And Methods Therewith | ESPINA VIRGINIA (US) | 2012-03-15 | — | — | US | disclosed |