Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DYRK1A | Q13627 | 1/20 | 0.39 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | HPGD | P15428 | 3/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.35 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | BLM | P54132 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | G6PD | P11413 | 1/20 | 0.35 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.35 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL439519 | 0.87 | DYRK1A (0.39) | DYRK1APDPK1ALDH1A1HPGDKDM4E | |
| SCHEMBL436999 | 0.86 | NQO2 (0.36) | DYRK1APDPK1ALDH1A1HPGDKDM4E | |
| SCHEMBL439833 | 0.81 | HAVCR2 (0.53) | ALDH1A1KDM4EMAPTNPC1RAB9A | |
| SCHEMBL437555 | 0.80 | HAVCR2 (0.38) | DYRK1AGAA | |
| SCHEMBL438246 | 0.76 | DPP4 (0.56) | MAPTNPC1RAB9AKMT2AMEN1 | |
| SCHEMBL438319 | 0.73 | NQO2 (0.36) | DYRK1APDPK1ALDH1A1HPGDKDM4E | |
| SCHEMBL441668 | 0.72 | GAA (0.41) | DYRK1APDPK1ALDH1A1KDM4EMAPT | |
| SCHEMBL436008 | 0.72 | HTR1A (0.44) | ALDH1A1KDM4EG6PD | |
| SCHEMBL437482 | 0.70 | CYP3A4 (0.35) | KDM4EMAPTKMT2AMEN1POLB | |
| SCHEMBL435825 | 0.69 | HAVCR2 (0.50) | ALDH1A1KDM4EMAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120065166-A1 | Bone Modulators And Methods Therewith | ESPINA VIRGINIA (US) | 2012-03-15 | — | — | US | disclosed |