Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.32 |
| ▸ | HTR1A | P08908 | 3/20 | 0.31 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.31 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.31 |
| ▸ | ACHE | P22303 | 1/20 | 0.31 |
| ▸ | PARP1 | P09874 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.30 |
| ▸ | ADRB3 | P13945 | 2/20 | 0.30 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.30 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.30 |
| ▸ | CCR5 | P51681 | 1/20 | 0.30 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4399335 | 1.00 | KMT2A (0.32) | KMT2AMCHR1HTR1ASLC6A4DYRK1A | |
| SCHEMBL4411341 | 0.91 | HTR1A (0.34) | KMT2AMCHR1HTR1ASLC6A4ACHE | |
| SCHEMBL915392 | 0.89 | KMT2A (0.40) | KMT2AHTR1ADYRK1AACHEPARP1 | |
| SCHEMBL913688 | 0.89 | KMT2A (0.40) | KMT2AHTR1ADYRK1AACHEPARP1 | |
| SCHEMBL4405956 | 0.89 | FAAH (0.34) | KMT2AMCHR1DYRK1AMEN1CCR5 | |
| SCHEMBL4406699 | 0.89 | KMT2A (0.34) | KMT2AMCHR1HTR1ASLC6A4ACHE | |
| SCHEMBL4396316 | 0.89 | KMT2A (0.34) | KMT2AMCHR1HTR1ASLC6A4ACHE | |
| SCHEMBL4396436 | 0.86 | DRD2 (0.33) | HTR1ASLC6A4ACHEADRB3ADRB2 | |
| SCHEMBL4410335 | 0.86 | MCHR1 (0.33) | KMT2AMCHR1HTR1ASLC6A4DYRK1A | |
| SCHEMBL4405858 | 0.86 | PARP1 (0.34) | KMT2AHTR1ASLC6A4DYRK1APARP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1720859-B1 | CHEMOKINE RECEPTOR ANTAGONISTS | NOVARTIS AG (CH) | 2009-12-23 | — | — | EP | claimed |