Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.66 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | CYP19A1 | P11511 | 3/20 | 0.45 |
| ▸ | RAB9A | P51151 | 4/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 2/20 | 0.41 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.41 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.41 |
| ▸ | RELA | Q04206 | 2/20 | 0.41 |
| ▸ | IDO1 | P14902 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | ATP4A | P20648 | 2/20 | 0.40 |
| ▸ | ATP4B | P51164 | 2/20 | 0.40 |
| ▸ | MPL | P40238 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30263272 | 0.79 | HSD17B10 (1.00) | HSD17B10LMNARAB9ASMN1; SMN2MAPT | |
| SCHEMBL39119 | 0.79 | HSD17B10 (1.00) | HSD17B10LMNARAB9ASMN1; SMN2MAPT | |
| SCHEMBL19626487 | 0.78 | HSD17B10 (0.66) | HSD17B10LMNARAB9ASMN1; SMN2MAPT | |
| SCHEMBL17336572 | 0.75 | RAB9A (0.66) | HSD17B10LMNACYP19A1RAB9ASMN1; SMN2 | |
| SCHEMBL30607532 | 0.74 | HSD17B10 (0.47) | HSD17B10LMNARAB9ASMN1; SMN2MAPK1 | |
| SCHEMBL24696020 | 0.74 | HSD17B10 (0.60) | HSD17B10LMNACYP19A1RAB9ASMN1; SMN2 | |
| SCHEMBL19625320 | 0.74 | HSD17B10 (0.60) | HSD17B10LMNARAB9ASMN1; SMN2MAPK1 | |
| SCHEMBL1914839 | 0.74 | HSD17B10 (0.60) | HSD17B10LMNARAB9AL3MBTL1MAPT | |
| SCHEMBL956221 | 0.72 | ALDH1A1 (0.61) | HSD17B10LMNARAB9ASMN1; SMN2MAPT | |
| SCHEMBL3772673 | 0.72 | CYP19A1 (0.58) | HSD17B10LMNACYP19A1RAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2054410-A2 | OXAZOLIDONE DERIVATIVES AS PR MODULATORS | Wyeth (US) | 2009-05-06 | — | — | EP | claimed |
| WO-2008021331-A2 | OXAZOLIDONE DERIVATIVES AS PR MODULATORS | WYETH (US) | 2008-02-21 | — | — | WO | claimed |