Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 4/20 | 1.00 |
| ▸ | MPL | P40238 | 3/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.55 |
| ▸ | RAB9A | P51151 | 9/20 | 0.52 |
| ▸ | MAPT | P10636 | 8/20 | 0.52 |
| ▸ | NPC1 | O15118 | 7/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.52 |
| ▸ | MEN1 | O00255 | 4/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.52 |
| ▸ | LMNA | P02545 | 2/20 | 0.52 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.52 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.52 |
| ▸ | RELA | Q04206 | 2/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.52 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | HK1 | P19367 | 1/20 | 0.50 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.50 |
| ▸ | THRB | P10828 | 1/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30263272 | 1.00 | HSD17B10 (1.00) | HSD17B10MPLALDH1A1RAB9AMAPT | |
| SCHEMBL12592152 | 0.80 | HSD17B10 (0.67) | HSD17B10MPLALDH1A1RAB9AMAPT | |
| SCHEMBL4367505 | 0.80 | HSD17B10 (0.67) | HSD17B10MPLALDH1A1RAB9AMAPT | |
| SCHEMBL4398658 | 0.79 | HSD17B10 (0.66) | HSD17B10MPLALDH1A1RAB9AMAPT | |
| SCHEMBL19626487 | 0.79 | HSD17B10 (0.66) | HSD17B10MPLALDH1A1RAB9AMAPT | |
| SCHEMBL31052414 | 0.78 | HSD17B10 (0.64) | HSD17B10MPLALDH1A1RAB9AMAPT | |
| SCHEMBL44739 | 0.77 | MPL (1.00) | HSD17B10MPLALDH1A1RAB9AMAPT | |
| SCHEMBL3835119 | 0.77 | HSD17B10 (0.62) | HSD17B10MPLALDH1A1RAB9AMAPT | |
| SCHEMBL8359999 | 0.77 | HSD17B10 (0.62) | HSD17B10MPLALDH1A1RAB9AMAPT | |
| SCHEMBL6686670 | 0.77 | TYR (0.66) | HSD17B10MPLALDH1A1RAB9AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 56 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0006368-B1 | 4-PHENYL-THIAZOLYL-2-OXAMATE DERIVATIVES, THEIR PREPARATION AND THEIR USE IN THE TREATMENT OF ASTHMA | PIERRE FABRE S.A. (FR) | 1981-11-18 | — | — | EP | claimed |
| US-12383560-B2 | Compounds and uses thereof | FOGHORN THERAPEUTICS INC. (US) | 2025-08-12 | — | — | US | disclosed |
| WO-2025129104-A1 | COMPOUNDS, COMPOSITIONS, AND METHODS OF USING THEREOF | SIONNA THERAPEUTICS INC. (US) | 2025-06-19 | — | — | WO | disclosed |
| US-20230212131-A1 | COLLAGEN 1 TRANSLATION INHIBITORS AND METHODS OF USE THEREOF | ANIMA BIOTECH INC. (US) | 2023-07-06 | — | — | US | disclosed |
| US-20230212131-A1 | COLLAGEN 1 TRANSLATION INHIBITORS AND METHODS OF USE THEREOF | ANIMA BIOTECH INC. (US) | 2023-07-06 | — | — | US | disclosed |
| US-20230212131-A1 | COLLAGEN 1 TRANSLATION INHIBITORS AND METHODS OF USE THEREOF | ANIMA BIOTECH INC. (US) | 2023-07-06 | — | — | US | disclosed |
| US-20230149414-A1 | COMPOUNDS AND USES THEREOF | FOGHORN THERAPEUTICS INC. | 2023-05-18 | — | — | US | disclosed |
| US-20230149414-A1 | COMPOUNDS AND USES THEREOF | FOGHORN THERAPEUTICS INC. | 2023-05-18 | — | — | US | disclosed |
| US-20230149414-A1 | COMPOUNDS AND USES THEREOF | FOGHORN THERAPEUTICS INC. | 2023-05-18 | — | — | US | disclosed |
| US-20230138480-A1 | COMPOUNDS AND USES THEREOF | FOGHORN THERAPEUTICS INC. | 2023-05-04 | — | — | US | disclosed |
| US-9073890-B2 | Therapeutic compounds and related methods of use | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2015-07-07 | — | — | US | disclosed |
| US-20130053341-A1 | THERAPEUTIC COMPOUNDS AND RELATED METHODS OF USE | OTSUKA PHARMACEUTICAL COMPANY (JP) | 2013-02-28 | — | — | US | disclosed |
| US-20130053341-A1 | THERAPEUTIC COMPOUNDS AND RELATED METHODS OF USE | OTSUKA PHARMACEUTICAL COMPANY (JP) | 2013-02-28 | — | — | US | disclosed |
| WO-2011151436-A2 | NOVEL COMPOUNDS, METHOD FOR USE THEM AND PHARMACEUTICAL COMPOSITION CONTAINING THEM | EUROSCREEN S.A. (BE) | 2011-12-08 | — | — | WO | disclosed |
| CN-100381936-C | Linked dihydrazone-based charge transport compounds | SAMSUNG ELECTRONICS CO LTD (KR) | 2008-04-16 | — | — | CN | disclosed |
| EP-1519235-B1 | Linked dihydrazone-based charge transport compounds | SAMSUNG ELECTRONICS CO LTD (KR) | 2007-07-11 | — | — | EP | disclosed |
| US-7074532-B2 | Linked dihydrazone-based charge transport compounds | SAMSUNG ELECTRONICS, CO., LTD. (KR) | 2006-07-11 | — | — | US | disclosed |
| EP-1519235-A2 | Linked dihydrazone-based charge transport compounds | Samsung Electronics Co., Ltd. (KR) | 2005-03-30 | — | — | EP | disclosed |
| CN-1598699-A | Linked dihydrazone-based charge transport compounds | SAMSUNG ELECTRONICS CO LTD (KR) | 2005-03-23 | — | — | CN | disclosed |
| US-20050058916-A1 | Linked dihydrazone-based charge transport compounds | S-PRINTING SOLUTION CO., LTD. (KR) | 2005-03-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230149414-A1 | COMPOUNDS AND USES THEREOF | VHL, CLN6, TFEB | HSD17B10 1370/4885MPL 2639/4885ALDH1A1 2571/4885 |
| US-20230212131-A1 | COLLAGEN 1 TRANSLATION INHIBITORS AND METHODS OF USE THEREOF | COL1A1, COL2A1, COL14A1 | HSD17B10 3757/4885MPL 3649/4885ALDH1A1 1209/4885 |
| US-20230138480-A1 | COMPOUNDS AND USES THEREOF | VHL, CLN6, TFEB | HSD17B10 1370/4885MPL 2639/4885ALDH1A1 2571/4885 |
| US-12383560-B2 | Compounds and uses thereof | VHL, CLN6, TFEB | HSD17B10 1370/4885MPL 2639/4885ALDH1A1 2571/4885 |
| US-20130053341-A1 | THERAPEUTIC COMPOUNDS AND RELATED METHODS OF USE | PPP4C, PPP3CB, PTPRG | HSD17B10 2306/4885MPL 645/4885ALDH1A1 2732/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.