Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
| ▸ | FABP4 | P15090 | 2/20 | 0.34 |
| ▸ | CA12 | O43570 | 3/20 | 0.33 |
| ▸ | CA9 | Q16790 | 3/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | HPGD | P15428 | 2/20 | 0.32 |
| ▸ | HTT | P42858 | 2/20 | 0.32 |
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.32 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.32 |
| ▸ | POLB | P06746 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL334907 | 0.80 | CA12 (0.39) | ALDH1A1KMT2ASMN1; SMN2TSHRKDM4E | |
| SCHEMBL1839511 | 0.76 | TSHR (0.47) | ALDH1A1KMT2ATSHRKDM4EMEN1 | |
| SCHEMBL8908414 | 0.72 | GAA (0.36) | ALDH1A1KMT2ASMN1; SMN2TSHRKDM4E | |
| SCHEMBL317655 | 0.69 | ALB (0.49) | ALDH1A1KMT2AFABP4CA12CA9 | |
| SCHEMBL4901236 | 0.66 | TLR9 (0.49) | ALDH1A1KDM4ECA12CA9CA1 | |
| SCHEMBL2293356 | 0.66 | ALDH1A1 (0.43) | ALDH1A1KMT2AMEN1LMNAHPGD | |
| SCHEMBL4766593 | 0.65 | GABRA1 (0.40) | ALDH1A1KMT2ASMN1; SMN2TSHRKDM4E | |
| SCHEMBL6006263 | 0.65 | TSHR (0.56) | ALDH1A1KMT2ATSHRKDM4EMEN1 | |
| SCHEMBL11351155 | 0.65 | BID (0.45) | KMT2ASMN1; SMN2KDM4EMAPTHSD17B10 | |
| Hexane SCHEMBL27656302 | 0.65 | TSHR (0.50) | ALDH1A1KMT2ATSHRKDM4EMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 68 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8574833-B2 | Methods and compositions for amplifying a detectable signal | GREAT BASIN SCIENTIFIC (US) | 2013-11-05 | — | — | US | claimed |
| US-9695232-B2 | Anti-ED-A immunoconjugates for inflammatory bowel disease | PHILOGEN S.P.A. (IT) | 2017-07-04 | — | — | US | disclosed |
| US-9539348-B2 | Monoclonal antibody DS6, tumor-associated antigen CA6, and methods of use thereof | EAST CAROLINA UNIVERSITY (US) | 2017-01-10 | — | — | US | disclosed |
| US-20150361161-A1 | ANTIGENS ASSOCIATED WITH INFLAMMATORY BOWEL DISEASE | PHILOGEN S.P.A. (IT) | 2015-12-17 | — | — | US | disclosed |
| US-20150297762-A1 | MONOCLONAL ANTIBODY DS6, TUMOR-ASSOCIATED ANTIGEN CA6, AND METHODS OF USE THEREOF | EAST CAROLINA UNIVERSITY (US) | 2015-10-22 | — | — | US | disclosed |
| US-8980220-B2 | Molecular probe for imaging of pancreatic islets and use of the same | KYOTO UNIVERSITY (JP) | 2015-03-17 | — | — | US | disclosed |
| US-8728741-B2 | Monoclonal antibody DS6, tumor-associated antigen CA6, and methods of use thereof | East Carolina Unversity (US) | 2014-05-20 | — | — | US | disclosed |
| US-20140134619-A1 | SYSTEMS AND METHODS FOR POINT-OF-CARE AMPLIFICATION AND DETECTION OF POLYNUCLEOTIDES | GREAT BASIN SCIENTIFIC (US) | 2014-05-15 | — | — | US | disclosed |
| US-8637250-B2 | Systems and methods for point-of-care amplification and detection of polynucleotides | GREAT BASIN SCIENTIFIC (US) | 2014-01-28 | — | — | US | disclosed |
| US-8574833-B2 | Methods and compositions for amplifying a detectable signal | GREAT BASIN SCIENTIFIC (US) | 2013-11-05 | — | — | US | disclosed |
| US-6426400-B1 | COMPLEXES | DUKE UNIVERSITY | 2002-07-30 | — | — | US | disclosed |
| WO-2002051448-A1 | ANTI-TENASCIN MONOCLONAL ANTIBODY THERAPY FOR LYMPHOMA | DUKE UNIVERSITY (US) | 2002-07-04 | — | — | WO | disclosed |
| WO-2002016401-A2 | MONOCLONAL ANTIBODY DS6, TUMOR-ASSOCIATED ANTIGEN CA6, AND METHODS OF USE THEREOF | EAST CAROLINA UNIVERSITY (US) | 2002-02-28 | — | — | WO | disclosed |
| EP-0728215-B1 | METHOD OF BINDING MATERIAL TO THE Beta-AMYLOID PEPTIDE | UNIV DUKE (US) | 2002-02-20 | — | — | EP | disclosed |
| EP-1135170-A2 | RADIOCONJUGATION OF INTERNALIZING ANTIBODIES | DUKE UNIVERSITY (US) | 2001-09-26 | — | — | EP | disclosed |
| US-6294340-B1 | Method of binding material to the β-amyloid peptide | DUKE UNIVERSITY | 2001-09-25 | — | — | US | disclosed |
| WO-2000032240-A2 | RADIOCONJUGATION OF INTERNALIZING ANTIBODIES | DUKE UNIVERSITY (US) | 2000-06-08 | — | — | WO | disclosed |
| US-5624659-A | Method of treating brain tumors expressing tenascin | DUKE UNIVERSITY (US) | 1997-04-29 | — | — | US | disclosed |
| US-5558852-A | Methods of treating melanomas and gliomas with monoclonal antibody Me1-14 | DUKE UNIVERSITY (US) | 1996-09-24 | — | — | US | disclosed |
| WO-1994021294-A1 | METHOD OF TREATING TUMORS WITH ANTIBODIES | BIGNER DARELL D (US) | 1994-09-29 | — | — | WO | disclosed |